TY - BOOK ID - 61122635 TI - Molecular Mechanism of Alzheimer's Disease PY - 2019 SN - 303921408X 3039214071 PB - MDPI - Multidisciplinary Digital Publishing Institute DB - UniCat KW - HOTAIR KW - neurosciences KW - sleep disturbance KW - positron emission tomography (PET) KW - vitamin B complex KW - neurodegeneration KW - Tau KW - miR-15/107 KW - default-mode network KW - complement receptor 1 KW - neuronal differentiation KW - epigenetics KW - brain glucose metabolism KW - oligomerization KW - genetic risk KW - A?O receptors KW - prion KW - ryanodine receptor KW - type 3 diabetes KW - complement KW - cognitive behavioral therapy for insomnia KW - cognitive function KW - epigenome-wide association study KW - Alzheimer’s disease KW - calcium signaling KW - ?-secretase KW - tau KW - Prolyl isomerases KW - NEAT1 KW - complement C3b/C4b receptor KW - proteostasis KW - amyloid beta KW - yeast KW - slow-wave sleep KW - amyloid ? KW - nutrition KW - 4 KW - protein aggregation KW - apolipoprotein E KW - dementia KW - MALAT1 KW - inositol 1 KW - lncRNAs KW - molecular biology KW - methylenetetrahydrofolate reductase MTHFR gene KW - 5-trisphosphate receptor KW - CR1 density KW - miR-34c KW - aggregation KW - heat shock protein KW - dendritic spine KW - S-adenosylmethionine KW - beta amyloid KW - ion channel KW - inflammation KW - sleep fragmentation KW - cystathionine-?-lyase CTH gene KW - DNA methylation KW - heat shock response KW - microglia KW - drug target discovery KW - amyloid-? oligomer KW - therapy KW - CR1 length polymorphism KW - methylome KW - APOE gene KW - ubiquitin KW - magnetic resonance imaging (MRI) KW - neuronal degeneration KW - type 2 diabetes KW - Pin1 KW - mild cognitive impairment KW - dairy products KW - endoplasmic reticulum KW - oxidative stress KW - Hispanics KW - CDK5R1 UR - https://www.unicat.be/uniCat?func=search&query=sysid:61122635 AB - Alzheimer’s disease (AD) is an age-related neurological disease that affects tens of millions of people, in addition to their carers. Hallmark features of AD include plaques composed of amyloid beta, as well as neurofibrillary tangles of tau protein. However, despite more than a century of study, the cause of Alzheimer’s disease remains unresolved. The roles of amyloid beta and tau are being questioned and other causes of AD are now under consideration. The contributions of researchers, model organisms, and various hypotheses will be examined in this Special Issue. ER -