TY - BOOK ID - 61122604 TI - The Interplay of Microbiome and Immune Response in Health and Diseases AU - Barceló-Coblijn, Gwendolyn AU - Amedei, Amedeo PY - 2019 SN - 3039216473 3039216465 PB - MDPI - Multidisciplinary Digital Publishing Institute DB - UniCat KW - gastrointestinal diseases KW - sterile inflammation KW - n/a KW - Staphylococcus spp. KW - etiopathogenesis KW - colitis KW - Escherichia coli KW - bacteriophages KW - atopic dermatitis KW - intravenous immunoglobulin G KW - adaptive immunity KW - 16S rRNA gene KW - vaginal microbiota KW - modularity KW - innate immunity KW - gut-liver axis KW - disease activity KW - immune system KW - cytokines KW - commensals KW - Staphylococcus aureus KW - dysbiosis KW - fecal transplantation KW - TLR mimicry KW - etanercept KW - dextran sulfate sodium KW - CAR T-cell KW - 3-dihydroxy-4-methoxyBenzaldehyde KW - chemo free treatment KW - Staphylococcus epidermis KW - rheumatoid arthritis KW - microbiome KW - co-occurrence network KW - immune epigenetics KW - 2 KW - autoimmunity KW - superoxide dismutase KW - precision medicine KW - metabolism KW - adoptive cell transfer (ACT) KW - gut barrier KW - antibiotics KW - checkpoint inhibitors KW - probiotics KW - microbiota KW - Candida albicans KW - Enterococcus faecalis KW - chronic liver diseases KW - TCR KW - anaerobic bacteria KW - HSV2 KW - bacteriocins KW - methotrexate KW - microbial interactions KW - T cells KW - virus KW - mice KW - lymphoid malignancies KW - HPV KW - macrophages KW - anti-TNF-? KW - inflammation KW - chondroitin sulfate disaccharide KW - immunotherapy KW - genomics KW - immuno-oncology KW - diet KW - aerobic bacteria KW - immunological niche KW - melanin KW - health KW - chemokines KW - gut microbiota KW - cutaneous immunity KW - HIV KW - TIL KW - cancer KW - global network UR - https://www.unicat.be/uniCat?func=search&query=sysid:61122604 AB - [Increasing evidence suggests that microbiota and especially the gut microbiota (the microbes inhabiting the gut including bacteria, archaea, viruses, and fungi) plays a key role in human physiology and pathology. Recent findings indicate how dysbiosis—an imbalance in the composition and organization of microbial populations—could severely impact the development of different medical conditions (from metabolic to mood disorders), providing new insights into the comprehension of diverse diseases, such as IBD, obesity, asthma, autism, stroke, diabetes, and cancer. Given that microbial cells in the gut outnumber host cells, microbiota influences human physiology both functionally and structurally. Microbial metabolites bridge various—even distant—areas of the organism by way of the immune and hormone system. For instance, it is now clear that the mutual interaction between the gastrointestinal tract and the brain (gut–brain axis), often involves gut microbiota, indicating that the crosstalk between the organism and its microbial residents represents a fundamental aspect of both the establishment and maintenance of healthy conditions. Moreover, it is crucial to recognize that beyond the intestinal tract, microbiota populates other host organs and tissues (e.g., skin and oral mucosa). We have edited this eBook with the aim of publishing manuscripts focusing on the impact of microbiota in the development of different diseases and their associated treatments.] ER -