TY - BOOK ID - 61121966 TI - Marine Glycobiology, Glycomics and Lectins PY - 2019 SN - 3039218212 3039218204 PB - MDPI - Multidisciplinary Digital Publishing Institute DB - UniCat KW - toxicity KW - anticoagulant activities KW - Portunus pelagicus KW - complement system KW - Fucus distichus subsp. evanescens KW - MytiLec-1 KW - DNA methyltransferases KW - malignant glioma KW - heparin KW - innate immunity KW - polysialic acid (polySia) KW - HddSBL KW - differentiation induction KW - phagocytosis KW - fucosylated glycosaminoglycan KW - Alzheimer’s disease KW - thermostable KW - amyloid-? KW - lectins KW - ?-secretase KW - fucoidan KW - oncolytic vaccinia virus KW - Marinomonas KW - viral replication KW - BACE1 KW - glioblastoma KW - bioactivity KW - Ehrlich ascites carcinoma KW - adverse effects KW - therapeutic effects KW - ERK KW - physicochemical characteristics KW - oligo-fucoidan KW - tandem duplication KW - lectin KW - galactooligosaccharides KW - recombinant KW - TTL KW - theoretical model KW - fucan sulfate KW - retinal pigment epithelium KW - glycosaminoglycan KW - ?-galactosidase KW - apoptosis-related genes KW - C1q KW - VEGF KW - nanomedical devices KW - epigenetic modification KW - nematocyst discharge process KW - Mytilus galloprovincialis KW - pattern recognition receptors KW - Pattalus mollis KW - transglycosylation KW - anti-viral KW - nematogalectin KW - heparan sulphate KW - oxidative stress KW - bivalve mollusks UR - https://www.unicat.be/uniCat?func=search&query=sysid:61121966 AB - Glycans (carbohydrate chains) of marine creatures are rich and diverse in polysaccharides, glycoproteins, and glycolipids. The chains that are metabolized by glycan-related enzymes (glycosyltransferases and glycosidases) are recognized by glycan-binding proteins (lectins) which regulate cellular processes such as growth, differentiation, and death. Marine glycomics that involves the genome and transcriptome accelerates our understanding of the evolution of glycans, glycan-related enzymes, and lectins. From 2017 to 2019, the Special Issue “Marine Glycobiology, Glycomics and Lectins” of the journal Marine Drugs published scientific articles and reviews, on the background of “glycobiology”—that is, glycan-based biosciences. The aim was to promote the discovery of novel biomolecules that contribute to drug development and clinical studies. This has great potential for establishing connections between the fields of both human health and marine life sciences.This book contains 11 scientific papers representing current topics in comprehensive glycosciences related to therapeutic agents from marine natural products, as outlined. ER -