TY - BOOK ID - 56715997 TI - Systems Biology in Cancer Research and Drug Discovery AU - Azmi, Asfar S AU - SpringerLink (Online service) PY - 2012 SN - 9789400748194 PB - Dordrecht Springer Netherlands DB - UniCat KW - Biomathematics. Biometry. Biostatistics KW - Biology KW - Human biochemistry KW - Oncology. Neoplasms KW - Biotechnology KW - medische biochemie KW - bio-informatica KW - biochemie KW - biologie KW - oncologie KW - biotechnologie KW - biometrie UR - https://www.unicat.be/uniCat?func=search&query=sysid:56715997 AB - Systems Biology in Cancer Research and Drug Discovery provides a unique collection of chapters, by world-class researchers, describing the use of integrated systems biology and network modeling in the cancer field where traditional tools have failed to deliver expected promise. This book touches four applications/aspects of systems biology (i) in understanding aberrant signaling in cancer (ii) in identifying biomarkers and prognostic markers especially focused on angiogenesis pathways (iii) in unwinding microRNAs complexity and (iv) in anticancer drug discovery and in clinical trial design. This book reviews the state-of-the-art knowledge and touches upon cutting edge newer and improved applications especially in the area of network modeling. It is aimed at an audience ranging from students, academics, basic researcher and clinicians in cancer research. This book is expected to benefit the field of translational cancer medicine by bridging the gap between basic researchers, computational biologists and clinicians who have one ultimate goal and that is to defeat cancer. ER -