TY - BOOK ID - 5451704 TI - Bioorganometallic Chemistry PY - 2006 SN - 9783540330479 354033047X 3540330496 PB - Berlin, Heidelberg : Springer Berlin Heidelberg : Imprint: Springer, DB - UniCat KW - Bioorganic chemistry. KW - Organometallic chemistry. KW - Chimie bioorganique KW - Chimie organométallique KW - Chemistry. KW - Chemistry, inorganic. KW - Chemistry, Organic. KW - Biochemistry. KW - Catalysis. KW - Organometallic Chemistry. KW - Inorganic Chemistry. KW - Biochemistry, general. KW - Medicinal Chemistry. KW - Organometallic compounds KW - Biochemistry KW - Organometallic Compounds KW - Organic Chemicals KW - Inorganic Chemicals KW - Chemicals and Drugs KW - Organic Chemistry KW - Animal Biochemistry KW - Chemistry KW - Human Anatomy & Physiology KW - Health & Biological Sciences KW - Physical Sciences & Mathematics KW - 66.095.7 KW - Reactions involving organometallic compounds. Grignard reactions KW - 66.095.7 Reactions involving organometallic compounds. Grignard reactions KW - Chemicals, Organic KW - Metalloorganic Compounds KW - Metallo-Organic Compounds KW - Compounds, Metallo-Organic KW - Compounds, Metalloorganic KW - Compounds, Organometallic KW - Metallo Organic Compounds KW - Chemicals, Inorganic KW - Metallo-organic compounds KW - Metalloids, Organic KW - Metalorganic compounds KW - Organometalloids KW - Biological chemistry KW - Chemical composition of organisms KW - Organisms KW - Physiological chemistry KW - Organic chemistry KW - Inorganic chemistry KW - Composition KW - Inorganic chemistry. KW - Medicinal chemistry. KW - Organic compounds KW - Biology KW - Medical sciences KW - Activation (Chemistry) KW - Chemistry, Physical and theoretical KW - Surface chemistry KW - Inorganic compounds KW - Organometallic chemistry . KW - Chemistry, Medical and pharmaceutical KW - Chemistry, Pharmaceutical KW - Drug chemistry KW - Drugs KW - Medical chemistry KW - Medicinal chemistry KW - Pharmacochemistry KW - Chemistry, Organometallic KW - Metallo-organic chemistry KW - Chemistry, Organic KW - Chemistry, Inorganic. KW - Pharmaceutical chemistry. UR - https://www.unicat.be/uniCat?func=search&query=sysid:5451704 AB - Bioorganometallic Chemistry has become a mature area of science and is comprehensively covered by leading experts in this book. Naturally occuring bioorganometallic complexes, such as vitamin B12 and recently discovered iron and nickel hydrogenases, including a possible role of the latter in the geochemical theory of the origin of life, are considered. The possible formation of carbene complexes of cytochrome P450 enzymes in various metabolisms of xenobiotics is also discussed. The bioorganometallic chemistry is considered to provide not only organometallic receptors such as polynuclear organometallic macrocycles for biologically interesting molecules but also ferrocene-peptide bioconjugates giving a peptidomimetic basis for protein folding. The medicinal properties of organometallic compounds are reviewed, with notable applications in the treatment and diagnosis of cancer and in the treatment of viral, fungal, bacterial and parasitic infections. Therefore the reader will get a balanced view of this rapidly developing and promising area. ER -