TY - BOOK ID - 5430600 TI - Pediatric inflammatory bowel disease AU - Mamula, Petar. AU - Markowitz, Jonathan E. AU - Baldassano, Robert N. PY - 2008 SN - 9780387734804 0387734805 9786611137489 1281137480 0387734813 9781281137487 9780387734811 PB - New York ; London : Springer, DB - UniCat KW - Inflammatory Bowel Diseases. KW - Adolescent. KW - Child. KW - Infant. KW - Inflammatory bowel diseases. KW - Children KW - Affections intestinales inflammatoires KW - Enfants KW - Diseases KW - Maladies KW - Infant KW - Inflammatory Bowel Diseases KW - Adolescent KW - Child KW - Age Groups KW - Intestinal Diseases KW - Gastroenteritis KW - Gastrointestinal Diseases KW - Persons KW - Digestive System Diseases KW - Named Groups KW - Gastroenterology KW - Medicine KW - Health & Biological Sciences KW - Gastroenteritis. KW - EPUB-LIV-FT LIVMEDEC LIVSANTE SPRINGER-B KW - Cholera morbus KW - Enterogastritis KW - Flu, Intestinal KW - Flu, Stomach KW - Gastrointestinal system KW - Intestinal flu KW - Stomach flu KW - IBD (Disease) KW - Inflammatory bowel disease KW - Intestines KW - Inflammation KW - Medicine. KW - Internal medicine. KW - Gastroenterology. KW - Pediatrics. KW - Medicine & Public Health. KW - Internal Medicine. KW - Alimentary canal KW - Medicine, Internal KW - Paediatrics KW - Pediatric medicine KW - Internal medicine KW - Digestive organs KW - Health and hygiene KW - Gastroenterology . UR - https://www.unicat.be/uniCat?func=search&query=sysid:5430600 AB - Pediatric Inflammatory Bowel Diseases (IBD) are the most common and most significant chronic disorders in Pediatric Gastroenterology. The onset of Crohn disease and ulcerative colitis in the first two decades of life presents a number of diagnostic and therapeutic challenges that are unique to pediatric patients. Although the studies available for pediatric diagnosis have improved dramatically in the past three decades, the improvement in technology alone cannot account for the increased frequency of IBD recognized in early childhood. While therapy for older patients has improved dramatically with the use of immunomodulators and the development of exciting biologic strategies, rarely if ever have comprehensive studies of the pharmacokinetics, safety and efficacy of any of the IBD medications been performed in pediatric patients. A number of excellent medications are not available in liquid preparations that can be swallowed by children, and others, such as timed-release formulations, are developed for delivery to an adult gastrointestinal tract. It is unfortunate that the care we provide to children is often an extrapolation of what is known about and available for adults with IBD. Pediatric patients with IBD face a number of unique challenges. The onset of disease before puberty can be devastating. Growth failure is a particularly difficult problem with potentially permanent consequences. Much of the pediatric specific research has focused on the role of nutritional therapy to treat growth failure and induce remission. ER -