TY - BOOK ID - 50847944 TI - Fatty Acids and Cardiometabolic Health AU - Wu, Jason AU - Marklund, Matti PY - 2019 SN - 3038978914 3038978906 PB - MDPI - Multidisciplinary Digital Publishing Institute DB - UniCat KW - coronary artery disease KW - n-6 fatty acids KW - ischemic heart disease KW - n-3 fatty acids KW - body weight KW - alternatively activated macrophages KW - type 2 cytokines KW - children KW - medium-chain triglyceride KW - fat KW - omega-3 PUFA KW - substitution models KW - obesity KW - EETs KW - arachidonic acid KW - blood pressure KW - Genome-wide association study (GWAS) KW - antioxidant KW - Mediterranean diet KW - Insulin sensitivity KW - PUFA KW - n-3 PUFA KW - long-chain triglyceride KW - fish oil KW - omega 3 KW - CAD KW - adipose tissue KW - FADS KW - blood lipids KW - hemodynamics KW - genotype KW - erucic acid KW - klotho KW - CYP450 eicosanoids KW - cardiometabolic disease KW - fibrosis KW - desaturase KW - EEQs KW - cohort study KW - lipid metabolism KW - fatty acid KW - metabolic disease KW - epidemiology KW - omega-3 KW - inflammation KW - docosapentaenoic acid KW - omega-6 PUFA KW - type 2 diabetes mellitus KW - diet KW - CKD KW - human KW - perivascular adipose tissue KW - seafood KW - cardiovascular disease KW - prospective cohort study KW - linoleic acid KW - low-fat diet KW - conjugated fatty acids KW - furan fatty acids KW - unsaturated fat KW - statins KW - fish KW - cholesterol ester KW - CHD KW - COPD UR - https://www.unicat.be/uniCat?func=search&query=sysid:50847944 AB - The impact of fat intake on hypercholesterolemia and related atherosclerotic cardiovascular diseases has been studied for decades. However, the current evidence base suggests that fatty acids also influences cardiometabolic diseases through other mechanisms including effects on glucose metabolism, body fat distribution, blood pressure, inflammation, and heart rate. Furthermore, studies evaluating single fatty acids have challenged the simplistic view of shared health effects within fatty acid groups categorized by degree of saturation. In addition, investigations of endogenous fatty acid metabolism, including genetic studies of fatty acid metabolizing enzymes, and the identification of novel metabolically derived fatty acids have further increased the complexity of fatty acids’ health impacts. This Special Issue aims to include original research and up-to-date reviews on genetic and dietary modulation of fatty acids, and the role and function of dietary and metabolically derived fatty acids in cardiometabolic health. ER -