TY - BOOK ID - 50054441 TI - Intrinsically disordered proteins PY - 2019 SN - 0128167327 0128163488 9780128167328 9780128163481 PB - London DB - UniCat KW - Proteins KW - Structure. KW - Intrinsically Disordered Proteins KW - Carrier Proteins. KW - Protein Conformation KW - physiology. KW - Conformation, Protein KW - Conformations, Protein KW - Protein Conformations KW - Protein Folding KW - Binding Protein KW - Binding Proteins KW - Transport Proteins KW - Protein, Binding KW - Proteins, Binding KW - Proteins, Carrier KW - Proteins, Transport KW - Protein Binding KW - Receptors, Transferrin KW - Carrier Protein KW - Transport Protein KW - Protein, Carrier KW - Protein, Transport UR - https://www.unicat.be/uniCat?func=search&query=sysid:50054441 AB - "Intrinsically Disordered Proteins: Dynamics, Binding, and Function thoroughly examines and ties together the fundamental biochemical functions of intrinsically disordered proteins (IDPs) and intrinsically disordered regions (IDRs), including signaling, binding, and regulation, with the methodology for study and the associated pathways for drug design and therapeutic intervention. The role of new mechanistic, computational, and experimental approaches in IDP study are explored in depth, with methods for the characterization of IDP dynamics; models, simulations, and mechanisms of IDP and IDR binding; and biological and medical implications of IDP dynamics prominently featured. Written and edited by leading scientists in the field, this book explores groundbreaking areas such as ensemble descriptions of IDPs and IDRs, single-molecule studies of IDPs and IDRs, IDPs and IDRs in membraneless organelles, and molecular mechanisms of fibrillation of IDPs. Intrinsically Disordered Proteins provides students and researchers in biochemistry, molecular biology, and applied microbiology with a comprehensive and updated discussion of the complex dynamics of IDPs and IDRs."-- ER -