TY - BOOK ID - 4803894 TI - The sarcomere and skeletal muscle disease PY - 2008 SN - 9780387848471 0387848460 9780387848464 1441927417 9786612361135 1282361139 0387848479 PB - New York : Austin, Tex. : Springer Science+Business Media ; Landes Bioscience, DB - UniCat KW - Biomedicine. KW - Biomedicine general. KW - Human Physiology. KW - Medicine. KW - Human physiology. KW - Médecine KW - Physiologie humaine KW - Muscles -- Diseases. KW - Muscles KW - Muscular Diseases KW - Sarcomeres KW - Muscle, Skeletal KW - Myofibrils KW - Organelles KW - Neuromuscular Diseases KW - Musculoskeletal Diseases KW - Muscle, Striated KW - Musculoskeletal System KW - Muscle Fibers, Skeletal KW - Diseases KW - Cytoplasmic Structures KW - Myocytes, Cardiac KW - Nervous System Diseases KW - Anatomy KW - Muscle Cells KW - Cytoplasm KW - Tissues KW - Cells KW - Intracellular Space KW - Cellular Structures KW - Musculoskeletal System Diseases KW - Medicine KW - Health & Biological Sciences KW - Diseases. KW - Myopathy KW - Human biology KW - Medical sciences KW - Physiology KW - Human body KW - Clinical sciences KW - Medical profession KW - Life sciences KW - Pathology KW - Physicians KW - Biomedicine, general. KW - Health Workforce UR - https://www.unicat.be/uniCat?func=search&query=sysid:4803894 AB - Although best known for its role in heart disease, the sarcomere--the fundamental unit of muscle contraction--is also involved in skeletal muscle diseases. Chapters in The Sarcomere and Skeletal Muscle Disease provide an up-to-date review of diseases caused by mutated proteins in the different sub-compartments of the sarcomere, document the techniques currently being used to investigate the pathobiological bases of the diseases, which remain largely unknown, and discuss possible therapeutic options. ER -