TY - BOOK ID - 46216901 TI - Cancer Metastasis AU - Yasemin Basbinar AU - Basbinar, Yasemin AU - Calibasi Kocal, Gizem PY - 2018 SN - 1789846331 1789846323 1838818014 PB - IntechOpen DB - UniCat KW - Metastasis. KW - Cancer KW - Cancer metastasis KW - Dissemination of cancer KW - Metastases KW - Metastatic cancer KW - Neoplasm metastasis KW - Spread of cancer KW - Tumor dissemination KW - Tumor metastasis KW - Tumor spread KW - Pathology KW - Cancer invasiveness KW - Cancer of unknown primary origin KW - Dissemination KW - Metastasis KW - Medicine KW - Gynecologic Oncology KW - Oncology KW - Health Sciences UR - https://www.unicat.be/uniCat?func=search&query=sysid:46216901 AB - Metastasis of cancer cells from primary tumor site to secondary locations is considered a late event in multistep tumorigenesis, and causes most cancer-related mortality. The process from the spreading of cancer cells to the seeding of newly formed tumor colonizations is governed by sequential events, including local invasion, intravasation into stroma and blood vessels, survival in circulation, extravasation, and colonization at secondary tumor sites. Cancer research provides information on the fate of metastatic cancer cells in each sequential movement or heterogeneous tumor microenvironment. However, the complexity of this mechanism remains the most stringent concept of cancer management. This book provides information for cancer researchers on metastatic phenotypes of cancer cells, and diverse promoting factors and molecular mechanisms of metastasis. ER -