TY - BOOK ID - 46215295 TI - Celiac Disease : From the Bench to the Clinic AU - Carlos Hernández-Lahoz AU - Rodrigo, Luis AU - Hernández-Lahoz, Carlos PY - 2019 SN - 1789850509 1789850495 1838817581 PB - IntechOpen DB - UniCat KW - Celiac disease. KW - Coeliac disease KW - Diarrhea KW - Digestive organs KW - Malabsorption syndromes KW - Diseases KW - Life Sciences KW - Clinical Immunology KW - Immunology and Microbiology KW - Pure Immunology UR - https://www.unicat.be/uniCat?func=search&query=sysid:46215295 AB - Celiac disease (CD) occurs in about 1% of people worldwide. Diagnosis rates are increasing due to a true rise in incidence, rather than increased awareness and detection. CD affects genetically susceptible individuals who are triggered by the ingestion of gluten. The disease has many clinical manifestations, ranging from severe to minimally symptomatic or non-symptomatic presentations. Diagnosis requires the presence of duodenal chronic inflammation, and most patients have circulating antibodies against tissue transglutaminase. Our understanding of the basic and clinical aspects of CD increases, which is as a major health problem of almost global occurrence. Case finding, distinguishing CD from other gluten-sensitive conditions, better care, and balanced use of resources are the current challenges. ER -