TY - BOOK ID - 37725019 TI - Proteomics PY - 2002 SN - 1280043571 9786610043576 0306468956 0792375653 PB - Boston, Massachusetts : Kluwer Academic Publishers, DB - UniCat KW - Proteins KW - Protein binding. KW - Gene expression. KW - DNA microarrays. KW - Post-translational modification. KW - Analysis. KW - Structure. KW - Biochemistry. KW - Human genetics. KW - Morphology (Animals). KW - Pharmacy. KW - Biochemistry, general. KW - Human Genetics. KW - Animal Anatomy / Morphology / Histology. KW - Animal anatomy. KW - Chemistry KW - Medicine KW - Drugs KW - Materia medica KW - Pharmacology KW - Animal anatomy KW - Animals KW - Biology KW - Physiology KW - Genetics KW - Heredity, Human KW - Human biology KW - Physical anthropology KW - Biological chemistry KW - Chemical composition of organisms KW - Organisms KW - Physiological chemistry KW - Medical sciences KW - Anatomy KW - Composition KW - Proteomics. KW - Molecular biology KW - DNA biochips KW - Microarrays, DNA KW - Biochips KW - Immobilized nucleic acids KW - Genes KW - Genetic regulation KW - Co-translational modification KW - Cotranslational modification KW - Modification, Post-translational KW - Post-translation protein modification KW - Post-translational protein modification KW - Posttranslation protein modification KW - Posttranslational modification KW - Posttranslational protein modification KW - Genetic translation KW - Binding, Protein KW - Biochemistry KW - Allosteric proteins KW - Radioligand assay KW - Expression KW - Synthesis UR - https://www.unicat.be/uniCat?func=search&query=sysid:37725019 AB - Proteomics is an introduction to the exciting new field of proteomics, an interdisciplinary science that includes biology, bioinformatics, and protein chemistry. The purpose of this book is to provide the active researcher with an overview of the types of questions being addressed in proteomics studies and the technologies used to address those questions. Key subjects covered in this book include: an assessment of the limitations of this approach and outlines new developments in mass spectrometry that will advance future research high-throughput recombinant DNA cloning methods used to systematically clone all of the open reading frames of an organism into plasmid vectors for large scale protein expression and functional studies such as protein-protein interactions with the two-hybrid system protein structure an overview of large-scale experimental attempts to determine the three-dimensional structures of representative sets of proteins computational approaches to determining the three-dimensional structure of proteins. Proteomics provides a starting point for researchers who would like a theoretical understanding of the new technologies in the field, and obtain a solid grasp of the fundamentals before integrating new tools into their experiments. Written with attention to detail, but without being overwhelmingly technical, Proteomics is a user-friendly guide needed by most biologists today. ER -