TY - BOOK ID - 33240262 TI - Autophagy in Health and Disease : Potential Therapeutic Approaches PY - 2018 SN - 3319981463 3319981455 PB - Cham : Springer International Publishing : Imprint: Humana, DB - UniCat KW - Cell death. KW - Cytology. KW - Autophagic vacuoles. KW - Autophagocytosis KW - Cell biology KW - Cellular biology KW - Biology KW - Cells KW - Cytologists KW - Cell degeneration KW - Death (Biology) KW - Cell cycle. KW - Cell physiology. KW - Pharmaceutical technology. KW - Metabolic diseases. KW - Cell Cycle Analysis. KW - Cell Physiology. KW - Pharmaceutical Sciences/Technology. KW - Metabolic Diseases. KW - Disorders of metabolism KW - Metabolic diseases KW - Metabolic disorders KW - Metabolism, Disorders of KW - Diseases KW - Pharmaceutical laboratory techniques KW - Pharmaceutical laboratory technology KW - Technology, Pharmaceutical KW - Technology KW - Cell function KW - Cytology KW - Physiology KW - Mitotic cycle KW - Nuclear cycle (Cytology) KW - Biological rhythms UR - https://www.unicat.be/uniCat?func=search&query=sysid:33240262 AB - This timely volume explores the impact of autophagy in various human diseases, emphasizing the cell biological aspects and focusing on therapeutic approaches to these diseases. The chapters cover autophagy and its potential applications on diseases ranging from obesity, osteoarthritis, pulmonary fibrosis, and inflammation, through ALS, Parkinson's, retinal degeneration, breast cancer, alcoholic liver disease and more. The final chapters round out the book with a discussion of autophagy in drug discovery and 'bench to bedside'. Chapters are contributed by leading authorities and describe the general concepts of autophagy in health and disease, marrying cell biology and pharmacology and covering: studies derived from preclinical experiments, manufacturing considerations,and regulatory requirements pertaining to drug discovery and manufacturing and production. This volume will be useful for basic scientists as well as already practicing clinicians and advanced graduate students. ER -