TY - BOOK ID - 32841926 TI - Drug Interactions in Infectious Diseases: Mechanisms and Models of Drug Interactions AU - Pai, Manjunath P. AU - Kiser, Jennifer J. AU - Gubbins, Paul O. AU - Rodvold, Keith A. PY - 2018 SN - 3319724223 3319724215 PB - Cham : Springer International Publishing : Imprint: Humana, DB - UniCat KW - Drug interactions. KW - Communicable diseases. KW - Medicine. KW - Pharmacy. KW - Pharmaceutical technology. KW - Infectious diseases. KW - Biomedicine. KW - Pharmaceutical Sciences/Technology. KW - Infectious Diseases. KW - Pharmaceutical laboratory techniques KW - Pharmaceutical laboratory technology KW - Technology, Pharmaceutical KW - Technology KW - Chemistry KW - Medicine KW - Drugs KW - Materia medica KW - Pharmacology KW - Clinical sciences KW - Medical profession KW - Human biology KW - Life sciences KW - Medical sciences KW - Pathology KW - Physicians KW - Contagion and contagious diseases KW - Contagious diseases KW - Infectious diseases KW - Microbial diseases in human beings KW - Zymotic diseases KW - Diseases KW - Infection KW - Epidemics KW - Interactions, Drug KW - Side effects KW - Emerging infectious diseases. KW - Emerging infections KW - New infectious diseases KW - Re-emerging infectious diseases KW - Reemerging infectious diseases KW - Communicable diseases UR - https://www.unicat.be/uniCat?func=search&query=sysid:32841926 AB - The 4th edition of Drug Interactions in Infectious Diseases is being split into two separate volumes – “Mechanisms and Models of Drug Interactions” and “Antimicrobial Drug Interactions”. This volume, “Mechanisms and Models of Drug Interactions,” delivers a text that enhances clinical knowledge of the complex mechanisms, risks, and consequences of drug interactions associated with antimicrobials, infection, and inflammation. The book provides a comprehensive review of basic clinical pharmacology with a focus on metabolism and transporter-mediated drug interactions. The chapters address materials that cannot be retrieved easily in the medical literature, including materials focused on the complex interrelationship of acute infection, inflammation, and the risk of drug interactions in the Drug-Cytokine chapter. The Food-Drug and Herb-Drug interactions chapters remain definitive resources. A new chapter on in vitro modeling of drug interactions is included along with updates on design and data analysis of clinical drug interaction studies. Authoritative discussion of models for regulatory decision-making on drug-drug interactions provides the necessary framework to aid antimicrobial drug development. This concise review of the mechanisms and models of drug interactions provides important insights to health care practitioners as well as scientists in drug development. ER -