TY - BOOK ID - 32841900 TI - Acute and Chronic Neural Stimulation via Mechano-Sensitive Ion Channels PY - 2018 SN - 3319690590 3319690582 PB - Cham : Springer International Publishing : Imprint: Springer, DB - UniCat KW - Engineering. KW - Nanoscale science. KW - Nanoscience. KW - Nanostructures. KW - Biomedical engineering. KW - Nanotechnology. KW - Biomedical Engineering. KW - Nanoscale Science and Technology. KW - Neural stimulation. KW - Magnetic nanoparticle hyperthermia. KW - Hyperthermia, Magnetic fluid KW - Hyperthermia, Magnetic nanoparticle KW - Hyperthermia, Magnetic nanoparticle-based KW - Magnetic fluid hyperthermia KW - Magnetic nanoparticle-based hyperthermia KW - MNH (Magnetic nanoparticle hyperthermia) KW - Thermotherapy KW - Nerve stimulation KW - Stimulation, Neural KW - Electric stimulation KW - Electrodiagnosis KW - Electrophysiology KW - Electrotherapeutics KW - Biomedical Engineering and Bioengineering. KW - Molecular technology KW - Nanoscale technology KW - High technology KW - Clinical engineering KW - Medical engineering KW - Bioengineering KW - Biophysics KW - Engineering KW - Medicine KW - Nanoscience KW - Physics KW - Nano science KW - Nanoscale science KW - Nanosciences KW - Science UR - https://www.unicat.be/uniCat?func=search&query=sysid:32841900 AB - This book describes the tools, developed by the author, for perturbing endogenous mechano-sensitive ion channels for magneto-mechanical neuro-modulation. He explores the ways in which these tools compare against existing ones such as electricity, chemicals, optogenetics, and techniques like thermos/magneto-genetics. The author also reports on two platforms—magnetic ratcheting and magnetic microfluidics for directed evolution and high throughput culture of magnetotactic bacteria—that produce high quality magnetic nanoparticles for biomedical applications like neural stimulations. This thesis was submitted to and approved by the University of California, Los Angeles. Introduces technology for non-invasive control of neural activities that offer deep tissue penetration and controllable dosage; Examines the effects of biomechanical forces on cellular functions; Explores how to improve the reproducibility and uptake of magnetic tools for non-invasive neural modulation. ER -