TY - BOOK ID - 25047635 TI - Communication within animal cells PY - 1992 SN - 0198547269 0198547277 9780198547266 PB - Oxford [etc.] : Oxford University Press, DB - UniCat KW - Animal biochemistry KW - Zoohistology. Zoocytology KW - Cell interaction. KW - Régulation cellulaire KW - Interaction KW - Cell interaction KW - Régulation cellulaire KW - Cellular control mechanisms KW - Cellular control mechanisms. KW - Cellules KW - Cellular signal transduction UR - https://www.unicat.be/uniCat?func=search&query=sysid:25047635 AB - The ordered growth and functioning of animal cells requires the transfer of information from one part of the cell to another. This information comes from a bewildering variety of sources, both within and outside the cell. Hormones, neurotransmitters, growth factors and extracellular metabolites interact with specific receptors on the plasma membrane or in the cytoplasm. Inside the cell, information is relayed by intracellular messengers, including cyclic nucleotides, inositol polyphosphates, diacylglycerol and calcium, and by GTP-binding proteins, protein kinases, and DNA-binding proteins. Finely balanced interactions between these different signalling pathways ensure that the required response occurs, and abnormalities in any of the components of the system can lead to a variety of diseases, including cancer. This textbook brings together and puts into perspective a large body of knowledge about intracellular signalling systems. Written in a clear and authoritative style, with many illustrations, it will be invaluable to students on advanced undergraduate and graduate courses. It also provides a detailed introduction to and review of this central topic for researchers in cell biology and related disciplines. ER -