TY - BOOK ID - 22147199 TI - Translational biology in medicine PY - 2014 SN - 1908818654 1907568425 1322478767 9781322478760 9781908818652 9781907568428 PB - Cambridge, UK Woodhead Publishing, an imprint of Elsevier DB - UniCat KW - Medicine, Experimental. KW - Medical innovations. KW - Innovations, Medical KW - Medicine KW - Medical technology KW - Technological innovations KW - Experimental medicine KW - Innovations KW - Research UR - https://www.unicat.be/uniCat?func=search&query=sysid:22147199 AB - The recent emphasis in biomedical research on translational biology and personalized medicine is revolutionizing conceptual and experimental approaches to understanding and improving human health. Translational Biology in Medicine begins with an introduction to experimental model systems for disease, such as cell lines, primary cells, stem cells and animal models for disease, followed by a systematic description of genetic and genomic profiling and biomarker validation currently used in biomedical research. Examples of translation studies that have used these models and methods are presented, ER -