TY - BOOK ID - 217751 TI - Sensitization of cancer cells for chemo/immuno/radio-therapy PY - 2008 SN - 128186157X 9786611861575 1597454745 1934115290 161737928X PB - Totowa, NJ : Humana Press, DB - UniCat KW - Radiation-sensitizing agents. KW - Drug resistance in cancer cells. KW - Antineoplastic agents KW - Effectiveness. KW - Anticancer agents KW - Antineoplastic drugs KW - Antineoplastics KW - Antitumor agents KW - Antitumor drugs KW - Cytotoxic drugs KW - Inhibitors, Neoplasm KW - Neoplasm inhibitors KW - Drugs KW - Cancer KW - Antitumor drug resistance KW - Cancer drug resistance KW - Drug resistance in cancer KW - Drug resistance in tumor cells KW - Cancer cells KW - Radiation KW - Radiosensitizing agents KW - Chemotherapy KW - Sensitizing agents KW - Oncology. KW - Oncology  . KW - Toxicology. KW - Immunology. KW - Cancer Research. KW - Pharmacology/Toxicology. KW - Immunobiology KW - Life sciences KW - Serology KW - Chemicals KW - Medicine KW - Pharmacology KW - Poisoning KW - Poisons KW - Tumors KW - Toxicology KW - Cancer research. KW - Pharmacology. KW - Drug effects KW - Medical pharmacology KW - Medical sciences KW - Pharmacy KW - Cancer research KW - Physiological effect UR - https://www.unicat.be/uniCat?func=search&query=sysid:217751 AB - Cancer chemotherapy can be traced back to the 1940’s and since then the world has witnessed the discovery and the important application of several new drugs. The successes of combination chemotherapy suggested that all cancers can be treated provided that the correct combination of drugs at the correct doses and correct intervals are established. However, with time, tumor cells develop mechanisms of resistance to apoptosis and no longer respond to the majority of cytotoxic therapies. Sensitization of Cancer Cells for Chemo/Immuno/Radio-therapy, edited by Benjamin Bonavida, reviews novel approaches developed to reverse tumor cell resistance to chemo/immuno/radio-therapy and the use of various sensitizing agents in combination with various cytotoxics. Such sensitizing agents target gene products that regulate resistance and therefore identify novel targets for drug development. This book also introduces several of the current approaches that have been developed by established investigators in the field that are aimed at overcoming resistance. This book is the first that compiles studies on tumor cell sensitization and is useful for students, scientists, clinicians and pharmaceutical companies. ER -