TY - BOOK ID - 216060 TI - Systems Biological Approaches in Infectious Diseases AU - Boshoff, Helena I. AU - Barry, Clifton E. PY - 2007 VL - v. 64 SN - 1280745827 9786610745821 3764375671 3764375663 PB - Basel : Birkhäuser Basel : Imprint: Birkhäuser, DB - UniCat KW - Communicable diseases KW - Drugs KW - Epidemiology KW - Mathematical models. KW - Design KW - Medicaments KW - Medications KW - Medicine (Drugs) KW - Medicines (Drugs) KW - Pharmaceuticals KW - Prescription drugs KW - Contagion and contagious diseases KW - Contagious diseases KW - Infectious diseases KW - Microbial diseases in human beings KW - Zymotic diseases KW - Medicine. KW - Molecular biology. KW - Biomedicine. KW - Molecular Medicine. KW - Bioactive compounds KW - Medical supplies KW - Pharmacopoeias KW - Chemotherapy KW - Materia medica KW - Pharmacology KW - Pharmacy KW - Diseases KW - Infection KW - Epidemics KW - Clinical sciences KW - Medical profession KW - Human biology KW - Life sciences KW - Medical sciences KW - Pathology KW - Physicians KW - Health Workforce KW - Molecular biochemistry KW - Molecular biophysics KW - Biochemistry KW - Biophysics KW - Biomolecules KW - Systems biology UR - https://www.unicat.be/uniCat?func=search&query=sysid:216060 AB - Systems biology is an emerging discipline that studies the underlying network structure and the dynamics of metabolism, cells or whole organisms. It aims to investigate all interacting components simultaneously and requires data from high throughput techniques. These data from the "omic" sciences are computed and used to build in silico models of biological systems that ultimately will prove to be an invaluable tool in drug development. This book brings together the various fields of functional genomics and systems biology that provide information on metabolic function with a special emphasis on the identification of drug targets. It includes practical examples from the various "omic" sciences as well as theoretical examples of how integrated knowledge of these sciences can be applied to drug discovery. It is of interest to researchers in the pharmaceutical drug discovery environment, as well as those in the academic field with an interest in the functional application of the "omic" sciences. ER -