TY - BOOK ID - 210139 TI - Molecular mechanisms of synaptogenesis AU - Dityatev, Alexander. AU - El-Husseini, Alaa. PY - 2006 SN - 1280716282 9786610716289 038732562X 0387325603 PB - New York, NY : Springer, DB - UniCat KW - Neural transmission. KW - Synapses. KW - Neurotransmitters. KW - Cytoskeletal proteins. KW - Presynaptic receptors. KW - Neurotransmitter receptors KW - Structural proteins KW - Proteins KW - Chemical nerve transmitters KW - Nerve transmitter substances KW - Neural transmitters KW - Neurohumors KW - Neuroregulators KW - Synaptic transmitters KW - Transmitters, Chemical nerve KW - Transmitters, Synaptic KW - Neurochemistry KW - Neural transmission KW - Nerve endings KW - Nerves KW - Neural circuitry KW - Synaptosomes KW - Nerve transmission KW - Nervous transmission KW - Neurotransmission KW - Synaptic transmission KW - Transmission of nerve impulses KW - Neurophysiology KW - Neurotransmitters KW - Neurosciences. KW - Neural sciences KW - Neurological sciences KW - Neuroscience KW - Medical sciences KW - Nervous system UR - https://www.unicat.be/uniCat?func=search&query=sysid:210139 AB - Molecular Mechanisms of Synaptogenesis is a compilation of recent exciting findings that summarizes the ever-expanding knowledge of how neuronal contacts develop in the normal brain and how their functions are affected in mental disorders. In the last decade, advances in molecular and cellular biology, combined with the development of sophisticated fluorescence microscopy tools to visualize synapses in live neurons, have revealed many intriguing and unexpected findings regarding the dynamics of synapse formation. Studies by a number of researchers have identified several critical protein components of synapses and shown the time course of their arrival at the synapse. Several molecules serve to hold the synaptic contacts between nerve cells and regulate their function. Imbalance in synaptic contact formation and function has been linked to psychiatric disorders such as schizophrenia, autism and mental retardation. The recent advances in basic research, summarized in Molecular Mechanisms of Synaptogenesis, may lay the necessary scientific groundwork to develop treatments targeting synaptogenesis, allowing us to improve the lives of people affected by brain disorders. This book will be an invaluable resource for neurobiologists taking their first steps in the expanding and exciting field of synaptogenesis. ER -