TY - BOOK ID - 207608 TI - RHO family GTPases PY - 2005 VL - 3 SN - 1280283823 9786610283828 1402034628 140203461X 9048168732 PB - Dordrecht ; [Great Britain] : Springer, DB - UniCat KW - Rho GTPases. KW - G proteins. KW - GTP-binding proteins KW - GTP regulatory proteins KW - Guanine nucleotide-binding proteins KW - Guanine nucleotide regulatory proteins KW - Membrane proteins KW - Rho G proteins KW - Rho GTP-binding proteins KW - G proteins KW - Guanosine triphosphatase KW - Cytology. KW - Enzymes. KW - Biochemistry. KW - Proteomics. KW - Oncology. KW - Medicine. KW - Cell Biology. KW - Enzymology. KW - Biochemistry, general. KW - Cancer Research. KW - Molecular Medicine. KW - Clinical sciences KW - Medical profession KW - Human biology KW - Life sciences KW - Medical sciences KW - Pathology KW - Physicians KW - Tumors KW - Molecular biology KW - Proteins KW - Biological chemistry KW - Chemical composition of organisms KW - Organisms KW - Physiological chemistry KW - Biology KW - Chemistry KW - Biocatalysts KW - Ferments KW - Soluble ferments KW - Catalysts KW - Enzymology KW - Cell biology KW - Cellular biology KW - Cells KW - Cytologists KW - Composition KW - Health Workforce KW - Cell biology. KW - Cancer research. KW - Molecular biology. KW - Molecular biochemistry KW - Molecular biophysics KW - Biochemistry KW - Biophysics KW - Biomolecules KW - Systems biology KW - Cancer research KW - Enzymes UR - https://www.unicat.be/uniCat?func=search&query=sysid:207608 AB - Humans contain more than 20 Rho type GTPases. This volume not only presents a detailed phylogenetic analysis of Rho proteins, but also discusses the possible origins of the human members. Such an analysis of human Rho GTPases has not previously been attempted. The book includes an overview of how Rho GTPases become activated which is complemented by an extensive Chapter by Darerca Owen and Helen Mott who unravel the beautiful molecular details given to us by the many structural studies of Rho GTPases. The key areas currently being investigated in relation to these ubiquitous proteins are described for both in vitro and in vivo systems. These are presented in a format that ensures the reader can approach the topic with minimal background knowledge, while ultimately bringing the subject to the level of an expert. Timely and highly authoritative, this volume illuminates newer findings, particularly as they relate to Rho proteins in vertebrate biology. ER -