TY - BOOK ID - 19493495 TI - Practical preimplantation genetic diagnosis PY - 2012 SN - 1447140893 9786613934383 1447140907 1283621932 PB - London ; New York : Springer, DB - UniCat KW - Preimplantation genetic diagnosis. KW - Human reproductive technology KW - Assisted human reproduction KW - Assisted conception KW - Conception KW - Human assisted reproduction KW - Human reproduction KW - Preembryo diagnosis KW - Preimplantation diagnosis KW - Technological innovations KW - Medicine. KW - Human genetics. KW - Laboratory medicine. KW - Gynecology. KW - Obstetrics. KW - Reproductive medicine. KW - Medicine & Public Health. KW - Reproductive Medicine. KW - Human Genetics. KW - Obstetrics/Perinatology. KW - Laboratory Medicine. KW - Medical technology KW - Reproductive technology KW - Prenatal diagnosis KW - Medical laboratories. KW - Obstetrics/Perinatology/Midwifery. KW - Diagnosis, Laboratory KW - Health facilities KW - Laboratories KW - Gynaecology KW - Medicine KW - Generative organs, Female KW - Maternal-fetal medicine KW - Genetics KW - Heredity, Human KW - Human biology KW - Physical anthropology KW - Human reproductive health KW - Human reproductive medicine KW - Reproductive medicine KW - Health KW - Diseases KW - Health aspects KW - Gynecology . KW - Clinical medicine KW - Clinical pathology KW - Diagnostic laboratory tests KW - Laboratory diagnosis KW - Laboratory medicine KW - Medical laboratory diagnosis KW - Diagnosis KW - Pathology UR - https://www.unicat.be/uniCat?func=search&query=sysid:19493495 AB - Although treatment remains the major goal in the control of genetic disease, this is not yet a reality for most inherited conditions. In the absence of radical treatment, preimplantation genetic diagnosis (PGD) offers the answer to the control of these inherited conditions by predicting reproductive outcome. PGD is now entering its third decade as an established procedure for genetic and assisted reproduction practices, with new and exciting developments changing the whole concept of prevention of congenital disorders. The availability of practical experience from tens of thousands of PGD cases makes it necessary to update the current information on its accuracy, reliability and safety.  The Second Edition of this successful book updates the progress in prevention of genetic disorders to demonstrate the important place of PGD in primary preventive measures and its increasing role in providing the whole range of reproduction options to couples at risk. In addition, it provides an extensive review of the most recent developments within the field of PGD including, PGD for expanding indications, such as de novo mutations, cancers, inherited cardiac diseases and combined PGD for single gene disorders, HLA typing and 24 chromosome testing in patients of advance reproductive age. This practical book is vital for all practitioners within the field of fertility, reproductive medicine and medical genetics. It will also be useful for those responsible for planning and organizing PGD services and provides a working manual for the establishment and performance of PGD in the framework of IVF and genetic practices.  . ER -