TY - BOOK ID - 17826770 TI - Computer analysis of sequence data AU - Griffin, Annette M. AU - Griffin, Hugh G. PY - 1994 VL - 24, 25 SN - 0896032469 0896032760 159259512X 1592595111 PB - Totowa, N.J. : Humana Press, DB - UniCat KW - Amino acid sequence KW - Nucleotide sequence KW - Data processing. KW - 577.212.3 KW - 57.088.5 KW - 57.081.2 KW - 57.081.2 Automation of biological experiments KW - Automation of biological experiments KW - 577.212.3 Nucleic acid base and sequence compositon. Experimental deciphering of genetic code. KW - Nucleic acid base and sequence compositon. Experimental deciphering of genetic code. KW - Methods and techniques for studying structures and properties of biological molecules KW - Séquence des acides aminés KW - Séquence nucléotidique KW - Data processing KW - Informatique KW - Amino acid sequence analysis KW - Analysis, Amino acid sequence KW - Peptide sequence KW - Peptide sequencing KW - Protein sequence KW - Protein sequencing KW - Sequence, Amino acid KW - Amino acids KW - Proteins KW - Sequence alignment (Bioinformatics) KW - Analysis KW - Cytology. KW - Cell Biology. KW - Cell biology KW - Cellular biology KW - Biology KW - Cells KW - Cytologists UR - https://www.unicat.be/uniCat?func=search&query=sysid:17826770 AB - DNA sequencing has become increasingly efficient over the years, resulting in an enormous increase in the amount of data gen- ated. In recent years, the focus of sequencing has shifted, from being the endpoint of a project, to being a starting point. This is especially true for such major initiatives as the human genome project, where vast tracts of DNA of unknown function are sequenced. This sheer volume of available data makes advanced computer methods ess- tial to analysis, and a familiarity with computers and sequence ana- sis software a vital requirement for the researcher involved with DNA sequencing. Even for nonsequencers, a familiarity with sequence analysis software can be important. For instance, gene sequences already present in the databases can be extremely useful in the design of cloning and genetic manipulation experiments. This two-part work on Analysis of Data is designed to be a practical aid to the researcher who uses computers for the acquisition, storage, or analysis of nucleic acid (and/or p- tein) sequences. Each chapter is written such that a competent sci- tist with basic computer literacy can carry out the procedure successfully at the first attempt by simply following the detailed pr- tical instructions that have been described by the author. A Notes section, which is included at the end of each chapter, provides advice on overcoming the common problems and pitfalls sometimes enco- tered by users of the sequence analysis software. Software packages for both the mainframe and personal computers are described. ER -