TY - BOOK ID - 17105591 TI - Protein Design AU - Guerois, Raphael. AU - de la Paz, Manuela López. PY - 2006 VL - 340 SN - 10643745 SN - 1588295850 9781588295859 9786610832279 1280832274 1597451169 PB - Totowa, NJ : Humana Press : Imprint: Humana, DB - UniCat KW - Protein engineering KW - Protein Engineering KW - Proteins KW - Protein Conformation KW - Protein Folding KW - methods KW - chemistry KW - Protein engineering. KW - Biophysical Processes KW - Biophysical Phenomena KW - Engineering, Protein KW - Protein design KW - Proteins. KW - Proteids KW - Biomolecules KW - Polypeptides KW - Proteomics KW - Biochemical engineering KW - Genetic engineering KW - Design KW - Biochemistry. KW - Biochemistry, general. KW - Biological chemistry KW - Chemical composition of organisms KW - Organisms KW - Physiological chemistry KW - Biology KW - Chemistry KW - Medical sciences KW - Composition KW - 577.122 KW - 577.122 Protein metabolism KW - Protein metabolism KW - Protein Folding, Globular KW - Folding, Globular Protein KW - Folding, Protein KW - Foldings, Globular Protein KW - Foldings, Protein KW - Globular Protein Folding KW - Globular Protein Foldings KW - Protein Foldings KW - Protein Foldings, Globular KW - Proteostasis KW - Protein Multimerization KW - Intrinsically Disordered Proteins KW - Conformation, Protein KW - Conformations, Protein KW - Protein Conformations KW - Protein Engineering - methods KW - Proteins - chemistry UR - https://www.unicat.be/uniCat?func=search&query=sysid:17105591 AB - Recent major advances in our understanding of modulating protein functions has led to the development of new methods and algorithms to predict and decipher how amino acid sequences shape three-dimensional structures. Protein Design: Methods and Applications presents the most up-to-date protein design and engineering strategies so that readers can undertake their own projects with a maximum chance of success. The authors present integrated computational approaches that require various degrees of computational complexity, and the major accomplishments that have been achieved in the design and structural characterization of helical peptides and proteins. Other topics of discussion include: design of structural elementary motifs, entire proteins, and interfaces of protein complexes, and of amyloidogenic polypeptides and amyloid inhibitors. Authoritative and cutting-edge, Protein Design: Methods and Applications will be of major interest to protein scientists, biochemists, and all experimentalists selecting the strategy most adaptable for their design problem. ER -