TY - BOOK ID - 14661265 TI - Progress in the Chemistry of Organic Natural Products 104 AU - Kinghorn, A. Douglas. AU - Falk, Heinz. AU - Gibbons, Simon. AU - Kobayashi, Jun'ichi. PY - 2017 SN - 3319456180 3319456164 PB - Cham : Springer International Publishing : Imprint: Springer, DB - UniCat KW - Chemistry. KW - Pharmaceutical technology. KW - Organic chemistry. KW - Medicinal chemistry. KW - Organic Chemistry. KW - Pharmaceutical Sciences/Technology. KW - Medicinal Chemistry. KW - Chemistry, Organic. KW - Pharmaceutical chemistry. KW - Clinical biochemistry. KW - Medical biochemistry KW - Pathobiochemistry KW - Pathological biochemistry KW - Chemistry, Medical and pharmaceutical KW - Chemistry, Pharmaceutical KW - Drug chemistry KW - Drugs KW - Medical chemistry KW - Medicinal chemistry KW - Pharmacochemistry KW - Organic chemistry KW - Chemistry KW - Biochemistry KW - Pathology KW - Biochemistry. KW - Biological chemistry KW - Chemical composition of organisms KW - Organisms KW - Physiological chemistry KW - Biology KW - Medical sciences KW - Pharmaceutical laboratory techniques KW - Pharmaceutical laboratory technology KW - Technology, Pharmaceutical KW - Technology KW - Composition KW - Pharmaceutics. UR - https://www.unicat.be/uniCat?func=search&query=sysid:14661265 AB - The first contribution describes apolar and polar molecular fossils and, in particular biomarkers, along the lines usually followed in organic chemistry textbooks, and points to their bioprecursors when available. Thus, the apolar compounds are divided in linear and branched alkanes followed by alicyclic compounds and aromatic and heterocyclic molecules, and, in particular, the geoporphyrins. The polar molecular fossils contain as functional groups or constituent units ethers, alcohols, phenols, carbonyl groups, flavonoids, quinones, and acids, or are polymers like kerogen, amber, melanin, proteins, or nucleic acids. The final sections discuss the methodology used and the fundamental processes encountered by the biomolecules described, including diagenesis, catagenesis, and metagenesis. The second contribution covers the distribution of phthalides in nature and the findings in the structural diversity, chemical reactivity, biotransformations, syntheses, and bioactivity of natural and semisynthetic phthalides. ER -