TY - THES ID - 146387738 TI - Synthesis and Characterization of N-Heterocyclic Carbene Precursors Derived from Caffeine and Theophylline AU - Schumacher, Manuel AU - Delaude, Lionel AU - Pirotte, Bernard AU - Luxen, André PY - 2019 PB - Liège Université de Liège (ULiège) DB - UniCat KW - caffeine KW - theophylline KW - NHC KW - N-heterocyclic carbene KW - Physique, chimie, mathématiques & sciences de la terre > Chimie UR - https://www.unicat.be/uniCat?func=search&query=sysid:146387738 AB - The aim of this study was to synthesize a set of non-symmetrical N-heterocyclic carbene precursors derived from caffeine, a cheap and abundant natural alkaloid, by alkylating this methylxanthine. Since it was only possible to methylate or ethylate caffeine, our project then focused on the synthesis of imidazolium salts derived from theophylline, another natural alkaloid similar to caffeine. The target compounds were obtained with decent to good yields. Symmetrical benzimidazolium salts were prepared in order to achieve a comparative study. ER -