TY - BOOK ID - 146361225 TI - Advances in Antifungal Development: Discovery of New Drugs and Drug Repurposing AU - Kim, Jong Heon AU - Cheng, Luisa W. AU - Land, Kirkwood PY - 2022 PB - Basel MDPI - Multidisciplinary Digital Publishing Institute DB - UniCat KW - Research & information: general KW - Biology, life sciences KW - nanoparticles KW - fungi KW - drug delivery systems KW - marine KW - biological synthesis KW - myconanotechnology KW - canesten KW - clotrimazole KW - vulvovaginal KW - vaginitis KW - mycosis KW - candidosis KW - yeast infection KW - candida KW - candida albicans KW - vaginal health KW - anticandidal activity KW - indazole KW - pyrazole KW - 3-phenyl-1H-indazole KW - drug design KW - acetylsalicylic acid (ASA, aspirin) KW - capsule KW - CAP64 KW - Cryptococcus KW - membrane potential (ΔΨM) KW - photodynamic treatment KW - photosensitiser KW - ultrastructure KW - drug repurposing KW - antifungals KW - repositioning KW - yeasts KW - emerging fungi KW - multidrug resistance KW - therapeutic alternatives KW - new targets KW - Candida auris KW - Aspergillus spp. KW - antifungal KW - beta-glucan KW - polycations KW - Galleria mellonella model KW - retinoids KW - Candida spp. KW - onychomycosis KW - Malassezia spp. KW - dermatophytes KW - microbiology KW - mycology KW - all-trans retinoic acid KW - Acanthamoeba KW - free-living ameba KW - Acanthamoeba keratitis KW - isavuconazonium sulfate KW - cyst KW - drug KW - drug discovery KW - drug targets KW - invasive aspergillosis treatment KW - invasive fungal infections KW - fission yeast KW - cell wall KW - β(1,3)-D-glucan synthase KW - antifungal drugs KW - echinocandin drugs KW - echinocandin resistance KW - Fks resistance hot spots KW - cytokinesis KW - septation KW - cell separation KW - cell integrity KW - cell lysis KW - sporotrichosis KW - Felis catus KW - quinones KW - hydrazones KW - zoonoses KW - host-directed drug therapy KW - azoles KW - polyenes KW - echinocandins KW - viral infections KW - azole KW - synergy KW - resistance KW - Candida KW - natural products KW - nanoparticles KW - fungi KW - drug delivery systems KW - marine KW - biological synthesis KW - myconanotechnology KW - canesten KW - clotrimazole KW - vulvovaginal KW - vaginitis KW - mycosis KW - candidosis KW - yeast infection KW - candida KW - candida albicans KW - vaginal health KW - anticandidal activity KW - indazole KW - pyrazole KW - 3-phenyl-1H-indazole KW - drug design KW - acetylsalicylic acid (ASA, aspirin) KW - capsule KW - CAP64 KW - Cryptococcus KW - membrane potential (ΔΨM) KW - photodynamic treatment KW - photosensitiser KW - ultrastructure KW - drug repurposing KW - antifungals KW - repositioning KW - yeasts KW - emerging fungi KW - multidrug resistance KW - therapeutic alternatives KW - new targets KW - Candida auris KW - Aspergillus spp. KW - antifungal KW - beta-glucan KW - polycations KW - Galleria mellonella model KW - retinoids KW - Candida spp. KW - onychomycosis KW - Malassezia spp. KW - dermatophytes KW - microbiology KW - mycology KW - all-trans retinoic acid KW - Acanthamoeba KW - free-living ameba KW - Acanthamoeba keratitis KW - isavuconazonium sulfate KW - cyst KW - drug KW - drug discovery KW - drug targets KW - invasive aspergillosis treatment KW - invasive fungal infections KW - fission yeast KW - cell wall KW - β(1,3)-D-glucan synthase KW - antifungal drugs KW - echinocandin drugs KW - echinocandin resistance KW - Fks resistance hot spots KW - cytokinesis KW - septation KW - cell separation KW - cell integrity KW - cell lysis KW - sporotrichosis KW - Felis catus KW - quinones KW - hydrazones KW - zoonoses KW - host-directed drug therapy KW - azoles KW - polyenes KW - echinocandins KW - viral infections KW - azole KW - synergy KW - resistance KW - Candida KW - natural products UR - https://www.unicat.be/uniCat?func=search&query=sysid:146361225 AB - This reprint describes recent advances made in the field of antifungal development, especially the discovery of new drugs and drug repurposing. The articles presented in this book provide useful information and insight for the development of new antifungal drugs or intervention strategies. The identification of new, safe molecules, and cellular targets, as well as the elucidation of their antifungal mechanisms of action, will further the effective control of fungal pathogens, especially those resistant to current therapeutic agents. ER -