TY - BOOK ID - 146333814 TI - Bacterial invasion of host cells PY - 2004 SN - 1107144124 1280457813 9786610457816 0511185979 0511185146 0511187823 0511313829 0511546270 0511186894 PB - Cambridge ; New York : Cambridge University Press, DB - UniCat KW - Microbial invasiveness. KW - Host-bacteria relationships. KW - Molecular microbiology. UR - https://www.unicat.be/uniCat?func=search&query=sysid:146333814 AB - This book concerns the intimate association between bacteria and host cells. Many bacterial pathogens are able to invade and survive within cells at mucosal membranes. Remarkably, the bacteria themselves orchestrate this process through the exploitation of host cellular signal transduction pathways. Intracellular invasion can lead to disruption of host tissue integrity and perturbation of the immune system. An understanding of the molecular basis of bacterial invasion and of host cell adaptation to intracellular bacteria will provide fundamental insights into the pathophysiology of bacteria and the cell biology of the host. The book details specific examples of bacteria that are masters of manipulation of eukaryotic cell signaling and relates these events to the broader context of host-pathogen interaction. Written by experts in the field, this book will be of interest to researchers and graduate students in microbiology, immunology, biochemistry, as well as molecular medicine and dentistry. ER -