TY - BOOK ID - 146253416 TI - Role of Natural Bioactive Compounds in the Rise and Fall of Cancers : Volume 2 PY - 2020 PB - Basel, Switzerland MDPI - Multidisciplinary Digital Publishing Institute DB - UniCat KW - Research & information: general KW - Biology, life sciences KW - berberine KW - signaling pathways KW - oncogenic cascades KW - TRAIL KW - microRNAs KW - cancer therapy KW - colon cancer cells KW - ethanol KW - Nrf2 KW - HO-1 KW - ER stress KW - autophagy KW - MMPs KW - formononetin KW - cancer KW - preclinical models KW - cell signaling KW - angiogenesis KW - nobiletin KW - colorectal cancer KW - chemoprevention KW - bioactivities KW - experimental therapeutics KW - HDAC KW - multiple myeloma KW - oleacein KW - breast cancer KW - persistent organic pollutants KW - breast cancer risk KW - breast cancer prognostic KW - systematic review KW - carrageenan KW - invasion KW - metastasis KW - RacGAP1 KW - radiotherapy KW - marine sponge KW - natural product KW - anticancer drug KW - oral cancer inhibition KW - phytochemicals KW - small organic agents KW - Piper eriopodon, alkenylphenols KW - human cancer cells KW - cell death KW - apoptosis KW - caspase-independent cell death KW - XIAP antagonists KW - XIAP-BIR3 domain KW - Calocedrus formosana KW - lung cancer KW - yatein KW - cell-cycle arrest KW - xenograft KW - isorhamnetin KW - G2/M arrest KW - ROS KW - AMPK KW - pancreatic cancer KW - epigallocatechin-3-gallate (EGCG) KW - gemcitabine KW - glycolysis KW - phosphofructokinase KW - natural polyphenols KW - anticancer activities KW - molecular mechanisms KW - Streptomyces KW - mangrove KW - anti-proliferative KW - colon cancer KW - epithelial mesenchymal transition KW - inflammation KW - malignant cancer KW - natural anti-inflammatory compounds KW - pro-resolving lipids KW - anticancer drugs KW - flavonoids KW - natural compounds KW - Xenopus laevis KW - AOM/DSS model KW - melanoma cells KW - nicotine KW - α9-nAChR KW - PD-L1 KW - STAT3 KW - gigantol KW - AKT KW - JAK/STAT KW - cancer stem cell KW - tumor maintenance KW - tumor density KW - proteomics KW - honokiol KW - anticancer KW - mechanism KW - signalling pathway KW - uterine sarcoma KW - fucoidan KW - isobolography KW - colchicine alkaloid KW - mesoporous silica nanoparticles KW - targeted delivery system KW - PD-1 immune checkpoint inhibitor and cancer immunotherapy KW - glucose transport KW - drugs KW - innate immunity KW - β-glucans KW - nutrition KW - immunotherapy KW - estrogen KW - estrogen receptor alpha KW - polyphenols KW - daidzein KW - daidzein metabolites KW - paclitaxel KW - breast cancer cells KW - obesity KW - renin-angiotensin system KW - eicosapentaenoic acid KW - adipocyte inflammation KW - olive leaf extract KW - oleuropein KW - Seahorse analysis KW - cancer metabolism KW - glycolytic markers KW - Malva pseudolavatera Webb & KW - Berthel. KW - acute myeloid leukemia KW - reactive oxygen species KW - brain cancer KW - gliomas KW - schwannomas KW - malignant tumors of the peripheral nerve sheath (MPNST) KW - neurofibromas KW - bioavailability KW - nanoparticle-based delivery systems KW - natural bioactive compound KW - gallic acid KW - EGFR signaling KW - p53 KW - EGCG KW - non-coding RNAs KW - anti-cancer drug KW - NSCLC KW - EGFR TKI KW - FASN inhibitors KW - resistance KW - berberine KW - signaling pathways KW - oncogenic cascades KW - TRAIL KW - microRNAs KW - cancer therapy KW - colon cancer cells KW - ethanol KW - Nrf2 KW - HO-1 KW - ER stress KW - autophagy KW - MMPs KW - formononetin KW - cancer KW - preclinical models KW - cell signaling KW - angiogenesis KW - nobiletin KW - colorectal cancer KW - chemoprevention KW - bioactivities KW - experimental therapeutics KW - HDAC KW - multiple myeloma KW - oleacein KW - breast cancer KW - persistent organic pollutants KW - breast cancer risk KW - breast cancer prognostic KW - systematic review KW - carrageenan KW - invasion KW - metastasis KW - RacGAP1 KW - radiotherapy KW - marine sponge KW - natural product KW - anticancer drug KW - oral cancer inhibition KW - phytochemicals KW - small organic agents KW - Piper eriopodon, alkenylphenols KW - human cancer cells KW - cell death KW - apoptosis KW - caspase-independent cell death KW - XIAP antagonists KW - XIAP-BIR3 domain KW - Calocedrus formosana KW - lung cancer KW - yatein KW - cell-cycle arrest KW - xenograft KW - isorhamnetin KW - G2/M arrest KW - ROS KW - AMPK KW - pancreatic cancer KW - epigallocatechin-3-gallate (EGCG) KW - gemcitabine KW - glycolysis KW - phosphofructokinase KW - natural polyphenols KW - anticancer activities KW - molecular mechanisms KW - Streptomyces KW - mangrove KW - anti-proliferative KW - colon cancer KW - epithelial mesenchymal transition KW - inflammation KW - malignant cancer KW - natural anti-inflammatory compounds KW - pro-resolving lipids KW - anticancer drugs KW - flavonoids KW - natural compounds KW - Xenopus laevis KW - AOM/DSS model KW - melanoma cells KW - nicotine KW - α9-nAChR KW - PD-L1 KW - STAT3 KW - gigantol KW - AKT KW - JAK/STAT KW - cancer stem cell KW - tumor maintenance KW - tumor density KW - proteomics KW - honokiol KW - anticancer KW - mechanism KW - signalling pathway KW - uterine sarcoma KW - fucoidan KW - isobolography KW - colchicine alkaloid KW - mesoporous silica nanoparticles KW - targeted delivery system KW - PD-1 immune checkpoint inhibitor and cancer immunotherapy KW - glucose transport KW - drugs KW - innate immunity KW - β-glucans KW - nutrition KW - immunotherapy KW - estrogen KW - estrogen receptor alpha KW - polyphenols KW - daidzein KW - daidzein metabolites KW - paclitaxel KW - breast cancer cells KW - obesity KW - renin-angiotensin system KW - eicosapentaenoic acid KW - adipocyte inflammation KW - olive leaf extract KW - oleuropein KW - Seahorse analysis KW - cancer metabolism KW - glycolytic markers KW - Malva pseudolavatera Webb & KW - Berthel. KW - acute myeloid leukemia KW - reactive oxygen species KW - brain cancer KW - gliomas KW - schwannomas KW - malignant tumors of the peripheral nerve sheath (MPNST) KW - neurofibromas KW - bioavailability KW - nanoparticle-based delivery systems KW - natural bioactive compound KW - gallic acid KW - EGFR signaling KW - p53 KW - EGCG KW - non-coding RNAs KW - anti-cancer drug KW - NSCLC KW - EGFR TKI KW - FASN inhibitors KW - resistance UR - https://www.unicat.be/uniCat?func=search&query=sysid:146253416 AB - Recent years have seen the idea of a close association between nutrition and the modulation of cancer development/progression reinforced. An increasing amount of experimental and epidemiological evidence has been produced supporting the concept that many different bioactive components of food (e.g. polyphenols, mono- and polyunsaturated fatty acids, methyl-group donors, etc.) may be implicated in either the promotion of or the protection against carcinogenesis. At the cellular level, such compounds can have an impact on different but sometimes intertwined processes, such as growth and differentiation, DNA repair, programmed cell death, and oxidative stress. In addition, compelling evidence is starting to build up of the existence of primary epigenetic targets of dietary compounds, such as oncogenic/oncosuppressor miRNAs or DNA-modifying enzymes, which in turn impair gene expression and function. Since there is a growing interest in the study of the biochemical and molecular role played by food components and its impact on cellular processes and/or gene expressions directed towards the fine-tuning of cancer phenotypes, in this Special Issue researchers contributed with either research or review articles presenting the latest findings on the intracellular pathways and mechanisms affected by natural bioactive dietary molecules. ER -