TY - BOOK ID - 146035985 TI - Chagas Disease AU - Heukelbach, Jorg AU - Ramos Jr., Alberto Novaes AU - de Sousa, Andrea Silvestre PY - 2021 PB - Basel, Switzerland MDPI - Multidisciplinary Digital Publishing Institute DB - UniCat KW - Medicine KW - Chagas disease KW - neglected tropical diseases KW - migration KW - healthcare rights KW - mucosal leishmaniasis KW - co-infection KW - antimoniate therapy KW - cardiomyopathy KW - myocardial fibrosis KW - myocardial sympathetic denervation KW - inflammation KW - sudden death KW - cardiac magnetic resonance KW - radionuclide imaging KW - SPECT-CT KW - PET-CT KW - heart disease KW - electrocardiogram KW - disease progression KW - stroke KW - risk assessment KW - Trypanosoma cruzi KW - Triatoma infestans KW - parasite prevalence KW - coprophagy KW - human illness KW - neglected tropical disease KW - global financing KW - annual funding KW - investments KW - disease notification KW - public policy KW - neglected topical diseases KW - healthcare access KW - chagasic cardiomyopathy KW - heart transplantation KW - Chagas disease reactivation KW - cardiac allograft rejection KW - treatment of reactivation KW - genome KW - parasite KW - neglected diseases KW - heart transplant KW - chagas disease reactivation KW - Cohort studies KW - Neglected diseases KW - Dynamic programming KW - cost of illness KW - premature KW - efficiency KW - organizational KW - life expectancy KW - American trypanosomiasis KW - Trypanosoma cruzi infection KW - public health KW - epidemiology KW - prevention and control KW - surveillance KW - clinical research KW - One Health KW - Chagas disease KW - neglected tropical diseases KW - migration KW - healthcare rights KW - mucosal leishmaniasis KW - co-infection KW - antimoniate therapy KW - cardiomyopathy KW - myocardial fibrosis KW - myocardial sympathetic denervation KW - inflammation KW - sudden death KW - cardiac magnetic resonance KW - radionuclide imaging KW - SPECT-CT KW - PET-CT KW - heart disease KW - electrocardiogram KW - disease progression KW - stroke KW - risk assessment KW - Trypanosoma cruzi KW - Triatoma infestans KW - parasite prevalence KW - coprophagy KW - human illness KW - neglected tropical disease KW - global financing KW - annual funding KW - investments KW - disease notification KW - public policy KW - neglected topical diseases KW - healthcare access KW - chagasic cardiomyopathy KW - heart transplantation KW - Chagas disease reactivation KW - cardiac allograft rejection KW - treatment of reactivation KW - genome KW - parasite KW - neglected diseases KW - heart transplant KW - chagas disease reactivation KW - Cohort studies KW - Neglected diseases KW - Dynamic programming KW - cost of illness KW - premature KW - efficiency KW - organizational KW - life expectancy KW - American trypanosomiasis KW - Trypanosoma cruzi infection KW - public health KW - epidemiology KW - prevention and control KW - surveillance KW - clinical research KW - One Health UR - https://www.unicat.be/uniCat?func=search&query=sysid:146035985 AB - Despite being described for the first time more than 110 years ago, Chagas disease (caused by the parasite Trypanosoma cruzi) persists as one of the most neglected tropical diseases. This persistent neglect of those affected by this disease is evidenced by the ongoing scientific evidence gaps, the difficulty of incorporating new diagnostic and treatment technologies into the market, and public health failures to ensure timely access to diagnosis and treatment associated with the development of consistent surveillance and control actions. As a result, there is a high burden of morbidity and mortality, and poor quality of life, poverty, stigma, and a fear of death persist for affected people, both in endemic areas in Latin America, and in non-endemic areas. This book spans a variety of disciplines and contributes significantly to reducing the gap in scientific knowledge on Chagas disease, towards achieving the Sustainable Development Goals by 2030. ER -