TY - BOOK ID - 145629857 TI - Botulinum Neurotoxins and Nervous System : Future Challenges for Novel Indications PY - 2020 PB - Basel, Switzerland MDPI - Multidisciplinary Digital Publishing Institute DB - UniCat KW - Medicine KW - botulinum toxin KW - limb tremors KW - muscle selection KW - biological effect KW - various cell types KW - neurotransmitter KW - dermatology KW - novel indication KW - botulinum neurotoxin KW - masticatory system KW - maxillofacial bone KW - dental occlusion KW - orthognathic surgery KW - sialorrhoea KW - drooling KW - salivary glands KW - swallowing KW - eccrine glands KW - onabotulinumtoxin A KW - incobotulinumtoxin A KW - botulinum neurotoxins KW - botulinum neurotoxin serotype A KW - heavy chain KW - botulinum neurotoxin serotype a heavy chain (BoNT/A HC) KW - spinal cord injury (SCI) KW - nerve regeneration KW - growth associated protein 43 (GAP-43) KW - superior cervical ganglion 10 (SCG10) KW - neuronal processes KW - neural regeneration KW - Schwann cells KW - glia KW - spinal cord KW - immunohistochemistry KW - allodynia KW - weight bearing KW - sciatic static index KW - walking track analysis KW - itch KW - SNARE KW - VAMP KW - mast cells KW - compound 48/80 KW - chloroquine KW - spasticity KW - botulinum toxin type A KW - appropriate treatment KW - Therapeutic Index KW - pruritus KW - antipruritic KW - clinical KW - experimental KW - BoNT/A KW - astroglia KW - interleukins KW - microglia KW - TLR2 KW - TLR4 KW - Snap-23 KW - pain KW - cerebral palsy KW - botulinum toxin A KW - complex regional pain syndrome KW - lumbar sympathetic ganglion block KW - chronic pelvic pain KW - overactive detrusor KW - vaginism KW - temporomandibular joint dislocation KW - lateral pterygoid muscle KW - botulinum toxin therapy KW - synaptic transmission KW - SNAP-25 KW - epilepsy KW - Parkinson's disease KW - neurotransmission blockade KW - electrical activity KW - prion disease KW - new indications KW - formulation KW - delivery KW - refractory chronic migraine KW - tension headache KW - medication overuse headache KW - prophylactic treatment KW - XEOMIN® KW - BTX KW - central neuropathic pain KW - spinal cord injury KW - post-stroke shoulder pain KW - mouse test KW - Clostridium tetani KW - botulinum antitoxin KW - food safety KW - abobotulinumtoxinA KW - upper limb spasticity KW - post-stroke KW - early use KW - ONTIME KW - clinical trial KW - human KW - urodynamics KW - botulinum neurotoxin-A KW - basal ganglia KW - interspecies differences in motor behavior KW - mouse KW - rat KW - interneurons KW - hand tremor KW - treatment KW - electromyography KW - kinematics KW - essential tremor KW - dystonic tremor KW - tremor KW - movement disorders KW - Botulinum toxin KW - upper limb biomechanics KW - joint biomechanics KW - diagnostic guidance KW - clinical decision support KW - spastic paresis KW - electrical stimulation KW - stroke management KW - rehabilitation KW - hand KW - botulinum toxin KW - limb tremors KW - muscle selection KW - biological effect KW - various cell types KW - neurotransmitter KW - dermatology KW - novel indication KW - botulinum neurotoxin KW - masticatory system KW - maxillofacial bone KW - dental occlusion KW - orthognathic surgery KW - sialorrhoea KW - drooling KW - salivary glands KW - swallowing KW - eccrine glands KW - onabotulinumtoxin A KW - incobotulinumtoxin A KW - botulinum neurotoxins KW - botulinum neurotoxin serotype A KW - heavy chain KW - botulinum neurotoxin serotype a heavy chain (BoNT/A HC) KW - spinal cord injury (SCI) KW - nerve regeneration KW - growth associated protein 43 (GAP-43) KW - superior cervical ganglion 10 (SCG10) KW - neuronal processes KW - neural regeneration KW - Schwann cells KW - glia KW - spinal cord KW - immunohistochemistry KW - allodynia KW - weight bearing KW - sciatic static index KW - walking track analysis KW - itch KW - SNARE KW - VAMP KW - mast cells KW - compound 48/80 KW - chloroquine KW - spasticity KW - botulinum toxin type A KW - appropriate treatment KW - Therapeutic Index KW - pruritus KW - antipruritic KW - clinical KW - experimental KW - BoNT/A KW - astroglia KW - interleukins KW - microglia KW - TLR2 KW - TLR4 KW - Snap-23 KW - pain KW - cerebral palsy KW - botulinum toxin A KW - complex regional pain syndrome KW - lumbar sympathetic ganglion block KW - chronic pelvic pain KW - overactive detrusor KW - vaginism KW - temporomandibular joint dislocation KW - lateral pterygoid muscle KW - botulinum toxin therapy KW - synaptic transmission KW - SNAP-25 KW - epilepsy KW - Parkinson's disease KW - neurotransmission blockade KW - electrical activity KW - prion disease KW - new indications KW - formulation KW - delivery KW - refractory chronic migraine KW - tension headache KW - medication overuse headache KW - prophylactic treatment KW - XEOMIN® KW - BTX KW - central neuropathic pain KW - spinal cord injury KW - post-stroke shoulder pain KW - mouse test KW - Clostridium tetani KW - botulinum antitoxin KW - food safety KW - abobotulinumtoxinA KW - upper limb spasticity KW - post-stroke KW - early use KW - ONTIME KW - clinical trial KW - human KW - urodynamics KW - botulinum neurotoxin-A KW - basal ganglia KW - interspecies differences in motor behavior KW - mouse KW - rat KW - interneurons KW - hand tremor KW - treatment KW - electromyography KW - kinematics KW - essential tremor KW - dystonic tremor KW - tremor KW - movement disorders KW - Botulinum toxin KW - upper limb biomechanics KW - joint biomechanics KW - diagnostic guidance KW - clinical decision support KW - spastic paresis KW - electrical stimulation KW - stroke management KW - rehabilitation KW - hand UR - https://www.unicat.be/uniCat?func=search&query=sysid:145629857 AB - This book collects 25 scientific articles from laboratories around the world, all of which use botulinum neurotoxins as the main protagonists of their studies. The use of botulinum neurotoxin in medicine, following its ability to inhibit the effects of various disorders of different etiology on the human organism, constitutes the main topic of each article presented here. This book, which is aimed at both students and medical professionals, attempts to summarize current knowledge about the use of botulinum toxin as a therapeutic agent in many diseases, ranging from spasticity to tremor, form motor dysfunction after stroke to neuropathic pain, from hyperactive muscle to migraine, and so on. Thanks to its simplified writing, accessible to an audience who may not be familiar with the mysteries of science, readers will get new insights into this biological toxin and its multiple applications, not simply relegated to its historical use to correct of face wrinkles. Both review and research articles are presented, not only concerning animal studies, but also clinical reports. This book will provide an up-to-date picture of the state-of-the-art of the possible development of novel applications of botulinum neurotoxins for future therapeutic purposes. ER -