TY - BOOK ID - 145152739 TI - Sodium Intake and Related Diseases AU - Strazzullo, Pasquale AU - Santini, Antonello AU - Lucarini, Massimo AU - Durazzo, Alessandra AU - Lombardi-Boccia, Ginevra AU - Sette, Stefania PY - 2022 PB - Basel MDPI - Multidisciplinary Digital Publishing Institute DB - UniCat KW - Research & information: general KW - Biology, life sciences KW - Food & society KW - tight junction KW - Na+ cotransport KW - leaky epithelia KW - blood pressure KW - inflammation KW - mineralocorticoid receptor KW - Rac1 KW - renal injury KW - salt-sensitive hypertension KW - salt intake KW - sodium KW - hypertension KW - cardiovascular risk KW - mortality KW - prognosis KW - salt KW - heart failure KW - ambulatory heart failure KW - epidemiological studies KW - MST3 KW - STK24 KW - high potassium KW - ENaC KW - NKCC2 KW - SPAK KW - OSR1 KW - WNK4 KW - tight junction KW - Na+ cotransport KW - leaky epithelia KW - blood pressure KW - inflammation KW - mineralocorticoid receptor KW - Rac1 KW - renal injury KW - salt-sensitive hypertension KW - salt intake KW - sodium KW - hypertension KW - cardiovascular risk KW - mortality KW - prognosis KW - salt KW - heart failure KW - ambulatory heart failure KW - epidemiological studies KW - MST3 KW - STK24 KW - high potassium KW - ENaC KW - NKCC2 KW - SPAK KW - OSR1 KW - WNK4 UR - https://www.unicat.be/uniCat?func=search&query=sysid:145152739 AB - It has been recognized that moderation in the use of salt (sodium chloride) prevents the tendency of blood pressure to increase with age. On the other hand, the abuse of salt frequently leads to increases in blood pressure and contributes to the development of hypertension, particularly in overweight or obese people, in people with diabetes, in the elderly, and in genetically predisposed subjects. This Special Issue aims to provide a better understanding of the relationship between sodium intake and related diseases, in particular: (i) the effect on health status and description of the biochemical processes involved; and (ii) the use of salt and related risks. The main topics are studies in the management and treatment of sodium-intake-related diseases, epidemiological studies of the relationship between salt intake and related diseases, focuses on the mechanism of action; delineation of the mechanisms of action, and in vitro and in vivo studies. ER -