TY - BOOK ID - 14307445 TI - Mesenchymal stromal cells : biology and clinical applications AU - Hematti, Peiman. AU - Keating, Armand. PY - 2013 SN - 1461457106 1461457114 1299197302 PB - New York : Springer, DB - UniCat KW - Adult stem cells -- Cytology. KW - Biology. KW - Stem cells. KW - Mesenchymal stem cells KW - Stem Cell Transplantation KW - Cell Transplantation KW - Transplantation KW - Surgical Procedures, Operative KW - Analytical, Diagnostic and Therapeutic Techniques and Equipment KW - Mesenchymal Stem Cell Transplantation KW - Biology KW - Health & Biological Sciences KW - Cytology KW - Mesenchymal stem cells. KW - Bone marrow stromal cells KW - Marrow stromal cells KW - MSCs (Mesenchymal stem cells) KW - Stromal cells, Bone marrow KW - Stromal cells, Marrow KW - Life sciences. KW - Biotechnology. KW - Cell biology. KW - Life Sciences. KW - Stem Cells. KW - Cell Biology. KW - Multipotent stem cells KW - Cytology. KW - Chemical engineering KW - Genetic engineering KW - Cell biology KW - Cellular biology KW - Cells KW - Cytologists KW - Colony-forming units (Cells) KW - Mother cells KW - Progenitor cells KW - Mesenchymal Stem Cells KW - Cell- and Tissue-Based Therapy. KW - Mesenchymal Stem Cell Transplantation. KW - physiology. KW - Transplantation, Mesenchymal Stem Cell KW - Stem Cell Transplantation, Mesenchymal KW - Therapy, Cell KW - Therapy, Tissue KW - Cell Therapy KW - Tissue Therapy KW - Cell and Tissue Based Therapy KW - Tissue Therapy, Historical KW - transplantation UR - https://www.unicat.be/uniCat?func=search&query=sysid:14307445 AB - Mesenchymal Stromal Cell (MSC) biology has been studied for more than 4 decades and the cells have been investigated for potential clinical applications for more than 15 years. Progress has become exponential over the past decade due mainly to the broad therapeutic potential of these cells.   However, MSC studies have also been subject to controversy and increasing scrutiny as new mechanisms of action are reported and ever-expanding therapeutic applications pursued. In this book, leading authorities from all over the world, who are actively involved in this field, provide state-of-the-art knowledge of the basic biology, translational requirements and latest clinical experience with MSCs.  This cutting edge book is the ideal resource for scientists and clinicians interested in pursuing an important and rapidly developing field of research that will eventually help patients and address urgent unmet medical needs. Features include: Coverage of the biology of MSCs, latest understanding of  mechanisms of action, and role in tissue homeostasis and regeneration Identifying the potential of MSCs in proceeding from bench to bedside from regulatory , GMP production, ethical and safety aspects Critical analysis of clinical studies and the potential of MSCs to treat a wide variety of human diseases and tissues.   . ER -