TY - BOOK ID - 14306546 TI - EndoCANNABINOIDS : actions at non-CB1/CB2 cannadinoid receptors AU - Abood, Mary E. AU - Sorensen, Roger G. AU - Stella, Nephi. PY - 2013 SN - 1461446686 1461446694 1283697181 1489988467 PB - New York : Springer, DB - UniCat KW - Cannabinoids -- Receptors. KW - Medicine. KW - Receptors, Cannabinoid. KW - Cannabinoids KW - Hormones KW - Receptors, G-Protein-Coupled KW - Biological Science Disciplines KW - Terpenes KW - Neurotransmitter Agents KW - Receptors, Cell Surface KW - Natural Science Disciplines KW - Molecular Mechanisms of Pharmacological Action KW - Hydrocarbons KW - Hormones, Hormone Substitutes, and Hormone Antagonists KW - Physiological Effects of Drugs KW - Disciplines and Occupations KW - Membrane Proteins KW - Pharmacologic Actions KW - Organic Chemicals KW - Proteins KW - Chemical Actions and Uses KW - Chemicals and Drugs KW - Amino Acids, Peptides, and Proteins KW - Pharmacology KW - Receptors, Cannabinoid KW - Endocannabinoids KW - Medicine KW - Health & Biological Sciences KW - Neurology KW - Therapeutic use KW - Physiological effect. KW - Receptors. KW - Human physiology. KW - Neurosciences. KW - Pharmacology. KW - Proteins. KW - Animal physiology. KW - Biomedicine. KW - Human Physiology. KW - Animal Physiology. KW - Pharmacology/Toxicology. KW - Cannabis KW - Hallucinogenic drugs KW - Cell receptors. KW - Toxicology. KW - Chemicals KW - Poisoning KW - Poisons KW - Animal physiology KW - Animals KW - Biology KW - Anatomy KW - Human biology KW - Medical sciences KW - Physiology KW - Human body KW - Neural sciences KW - Neurological sciences KW - Neuroscience KW - Nervous system KW - Cell membrane receptors KW - Cell surface receptors KW - Receptors, Cell KW - Binding sites (Biochemistry) KW - Cell membranes KW - Toxicology KW - Proteins . KW - Drug effects KW - Medical pharmacology KW - Chemotherapy KW - Drugs KW - Pharmacy KW - Proteids KW - Biomolecules KW - Polypeptides KW - Proteomics KW - Physiological effect UR - https://www.unicat.be/uniCat?func=search&query=sysid:14306546 AB - The cloning of two G protein-coupled cannabinoid receptors, termed CB1 and CB2, in the early 1990s has stimulated and facilitated research conducted on the physiological function of cannabinoid actions in the brain and throughout the body. In the twenty years since the identification of these two receptors, endogenous ligands (endocannabinoids) for these receptors have been identified, their biosynthetic and metabolic pathways have been discerned, and their functional and regulatory action for signalling through CB1 and CB2 receptors have been described. More recently, it has become has become evident that cannabinoids exert actions at non-CB1, non-CB2 receptors. Much less is understood about these actions. Many of these novel “targets” are in the process of being characterized functionally and physiologically, and the therapeutic value of targeting these non-CB1, non-CB2 receptors is being evaluated. The purpose of this volume is to present the current knowledge on the atypical actions of cannabinoids on these new targets. This book is intended as a scientific resource for cannabinoid researchers carrying out animal and human experiments, and for those who are interested in learning about future directions in cannabinoid research. Additionally, this book may be of value to investigators currently working outside the field of cannabinoid research who have an interest in learning about these compounds and their atypical cannabinoid signalling. This book provides insight into the potential medical application of cannabinoids and their therapeutic development for the treatment of human disease. ER -