TY - BOOK ID - 14305088 TI - Bacterial Chromatin AU - Dame, Remus T. AU - Dorman, Charles J. PY - 2010 SN - 9048134722 9786612924668 9048134730 1282924664 9400790880 PB - Dordrecht : Springer Netherlands : Imprint: Springer, DB - UniCat KW - Bacterial chromatin -- Congresses. KW - Bacterial chromatin. KW - Bacterial Proteins. KW - Chromatin. KW - Nucleoproteins -- Congresses. KW - Bacterial chromatin KW - Bacterial Structures KW - Chromosome Structures KW - Chromosomes KW - Nucleoproteins KW - DNA KW - Proteins KW - DNA, Bacterial KW - Chromosomes, Bacterial KW - Chromatin KW - Bacterial Proteins KW - Genetic Structures KW - Cellular Structures KW - Amino Acids, Peptides, and Proteins KW - Anatomy KW - Nucleic Acids KW - Genetic Phenomena KW - Chemicals and Drugs KW - Nucleic Acids, Nucleotides, and Nucleosides KW - Cells KW - Intranuclear Space KW - Phenomena and Processes KW - Cell Nucleus Structures KW - Cell Nucleus KW - Intracellular Space KW - Biology KW - Microbiology & Immunology KW - Health & Biological Sciences KW - Life sciences. KW - Biochemistry. KW - Microbiology. KW - Bacteriology. KW - Biophysics. KW - Biological physics. KW - Life Sciences. KW - Biochemistry, general. KW - Biomedicine general. KW - Biophysics and Biological Physics. KW - Medicine. KW - Biological and Medical Physics, Biophysics. KW - Microbiology KW - Clinical sciences KW - Medical profession KW - Human biology KW - Life sciences KW - Medical sciences KW - Pathology KW - Physicians KW - Biological chemistry KW - Chemical composition of organisms KW - Organisms KW - Physiological chemistry KW - Chemistry KW - Microbial biology KW - Microorganisms KW - Composition KW - Biomedicine, general. KW - Health Workforce KW - Biological physics KW - Physics KW - Medicine KW - Bacteria. KW - Biomedical Research. KW - Research. KW - Germs KW - Microbes KW - Prokaryotes KW - Biological research KW - Biomedical research UR - https://www.unicat.be/uniCat?func=search&query=sysid:14305088 AB - The relative simplicity of the bacterial cell, short generation times and well defined and inexpensive culturing conditions have significantly contributed to our understanding of many complex biological systems. Yet the workings of the bacterial genome, seemingly impossibly compressed within a tiny nucleoid, have remained elusive. How is it that bacteria are able to package their genetic information within the confined space of the nucleoid while at the same time making it accessible for gene expression and DNA replication? This book, featuring the latest research by leading experts, describes the advanced methods being applied to the problem and shows how their work is contributing to our growing understanding of the ways that bacterial DNA storage, replication, recombination and gene expression are managed and coordinated. With due consideration paid to archaea and eukaryotes, the authors show how evolution in bacteria has provided solutions to these problems that range from the very sophisticated to the surprisingly simple. This comprehensive overview of bacterial chromatin clearly defines the fundamental concepts and goes on to show how cells inherit both chromosomal and extra-chromosomal genetic information at cell division. Several chapters are devoted to the central role played by nucleoid-associated proteins, with specific material on imaging the nucleoids, the physics of their structure and segregation, and the transcriptional regulation conducted by nucleoid-associated proteins. No other book currently available provides such a complete picture of these essential cellular processes. ER -