TY - BOOK ID - 14303510 TI - Prospects for chemoprevention of colorectal neoplasia : emerging role of anti-inflammatory drugs AU - Chan, Andrew T. AU - Detering, Elmar. PY - 2012 SN - 3642303307 9786613942630 3642303315 1283630184 3642434479 PB - Berlin ; Heidelberg : Springer, DB - UniCat KW - Cancer. KW - Colon (Anatomy) -- Cancer. KW - Colorectal neoplasia. KW - Colon (Anatomy) KW - Rectum KW - Anti-inflammatory agents KW - Therapeutic Uses KW - Intestinal Neoplasms KW - Neoplasms KW - Drug Therapy KW - Colonic Diseases KW - Rectal Diseases KW - Intestinal Diseases KW - Pharmacologic Actions KW - Therapeutics KW - Diseases KW - Gastrointestinal Neoplasms KW - Digestive System Neoplasms KW - Gastrointestinal Diseases KW - Chemical Actions and Uses KW - Analytical, Diagnostic and Therapeutic Techniques and Equipment KW - Digestive System Diseases KW - Neoplasms by Site KW - Chemicals and Drugs KW - Colorectal Neoplasms KW - Chemoprevention KW - Rectal Neoplasms KW - Colonic Neoplasms KW - Precancerous Conditions KW - Anti-Inflammatory Agents KW - Medicine KW - Health & Biological Sciences KW - Oncology KW - Cancer KW - Anti-inflammatory agents. KW - Treatment. KW - Anti-inflammatories KW - Antiinflammatory agents KW - Antiphlogistics KW - Medicine. KW - Internal medicine. KW - Cardiology. KW - Gastroenterology. KW - Oncology. KW - Medicine & Public Health. KW - Internal Medicine. KW - Colorectal Surgery. KW - Surgery. KW - Tumors KW - Internal medicine KW - Digestive organs KW - Heart KW - Medicine, Internal KW - Clinical sciences KW - Medical profession KW - Human biology KW - Life sciences KW - Medical sciences KW - Pathology KW - Physicians KW - Antipyretics KW - Inflammation KW - Oncology . KW - Gastroenterology . KW - Rectum—Surgery . UR - https://www.unicat.be/uniCat?func=search&query=sysid:14303510 AB - The prevention of colorectal cancer is a subject of increasing medical importance, and there have been a number of promising recent developments. This book examines in detail important aspects of the current status and future prospects for chemoprevention of colorectal tumors. Research into the mechanisms that lead from early colorectal adenoma to colorectal cancer is discussed. The role and modes of action of available drugs such as celecoxib and sulindac are described, and recent data from aspirin trials are analyzed. In addition, the possible impact of nutritional agents with anti-inflammatory properties is considered, and strategies applicable in those with a high level of genetic risk are evaluated. An important feature of the book is its holistic perspective, making it relevant for gastroenterologists, internists, general practitioners, oncologists, colorectal and gastroenterological surgeons, and public health practitioners. ER -