TY - BOOK ID - 14302750 TI - Diagnostic and prognostic biomarkers and therapeutic targets in melanoma PY - 2012 SN - 1607614324 9786613446534 1283446537 1607614332 PB - New York : Humana Press, DB - UniCat KW - Biochemical markers. KW - Melanoma -- Pathogenesis. KW - Melanoma KW - Tumor markers KW - Therapeutics KW - Neuroendocrine Tumors KW - Drug Discovery KW - Nevi and Melanomas KW - Biological Markers KW - Analytical, Diagnostic and Therapeutic Techniques and Equipment KW - Chemistry, Pharmaceutical KW - Neuroectodermal Tumors KW - Biological Factors KW - Investigative Techniques KW - Neoplasms by Histologic Type KW - Pharmacology KW - Chemicals and Drugs KW - Neoplasms, Nerve Tissue KW - Neoplasms KW - Chemistry KW - Neoplasms, Germ Cell and Embryonal KW - Diseases KW - Biological Science Disciplines KW - Natural Science Disciplines KW - Disciplines and Occupations KW - Drug Design KW - Drug Therapy KW - Tumor Markers, Biological KW - Drug Delivery Systems KW - Diagnosis KW - Medicine KW - Health & Biological Sciences KW - Oncology KW - Pathology KW - Diagnostic use KW - Treatment. KW - Biologic markers KW - Biological markers KW - Biomarkers KW - Markers, Biochemical KW - Malignant melanoma KW - Melanocytic tumor KW - Medicine. KW - Dermatology. KW - Oncology. KW - Pathology. KW - Medicine & Public Health. KW - Biochemistry KW - Indicators (Biology) KW - Cancer KW - Neuroendocrine tumors KW - Oncology  . KW - Skin KW - Tumors KW - Disease (Pathology) KW - Medical sciences KW - Medicine, Preventive UR - https://www.unicat.be/uniCat?func=search&query=sysid:14302750 AB - This book describes both the technologies used in the discovery of melanoma biomarkers and the clinical application of these biomarkers for diagnosis and staging of disease, determination of prognosis, treatment planning, monitoring of response to therapy, identification of novel therapeutic targets and drug development. A broad range of biomarkers (DNA/chromosomal, mRNA, microRNA, mitochondrial DNA, epigenetic and protein) is outlined. As therapies for melanoma become increasingly more target specific, the identification, validation and use of biomarkers will invariably play a greater role in the management of patients with this disease. Diagnostic and Prognostic Biomarkers and Therapeutic Targets in Melanoma is an essential resource for oncologists, dermatologists, dermatopathologists, general pathologists with an interest in melanoma, and melanoma researchers. ER -