TY - BOOK ID - 14302616 TI - Diabetes & C-peptide : scientific and clinical aspects PY - 2012 SN - 1617793906 9786613447708 1283447703 1617793914 PB - New York : Humana Press, DB - UniCat KW - C-peptide. KW - Diabetes. KW - Diabetes -- Complications. KW - Diabetes KW - C-peptide KW - Diabetes Mellitus KW - Proinsulin KW - Therapeutics KW - Autoimmune Diseases KW - Biological Science Disciplines KW - Analytical, Diagnostic and Therapeutic Techniques and Equipment KW - Immune System Diseases KW - Pancreatic Hormones KW - Endocrine System Diseases KW - Glucose Metabolism Disorders KW - Natural Science Disciplines KW - Peptide Hormones KW - Diseases KW - Disciplines and Occupations KW - Metabolic Diseases KW - Peptides KW - Nutritional and Metabolic Diseases KW - Hormones KW - Hormones, Hormone Substitutes, and Hormone Antagonists KW - Amino Acids, Peptides, and Proteins KW - Chemicals and Drugs KW - Physiology KW - Diabetes Mellitus, Type 1 KW - Drug Therapy KW - C-Peptide KW - Diabetes Complications KW - Medicine KW - Health & Biological Sciences KW - Clinical Endocrinology KW - Complications KW - Brittle diabetes KW - Diabetes mellitus KW - IDDM (Disease) KW - Insulin-dependent diabetes KW - Ketosis prone diabetes KW - Type 1 diabetes KW - Connecting peptide KW - Medicine. KW - Internal medicine. KW - Endocrinology. KW - Medicine & Public Health. KW - Internal Medicine. KW - Carbohydrate intolerance KW - Endocrine glands KW - Diabetic acidosis KW - Glycosylated hemoglobin KW - Medicine, Internal KW - Internal medicine KW - Endocrinology . UR - https://www.unicat.be/uniCat?func=search&query=sysid:14302616 AB - In Diabetes & C-Peptide: Scientific and Clinical Aspects, a renowned group of leading researchers and physicians offers a comprehensive overview of the role of C-Peptide in type 1 diabetes. The book is organized in five sections. An Introductory section provides the background and key features of C-peptide’s physiological function and how its deficiency contributes to complications. The second section describes up-to-date information on the biochemical and molecular actions of C-peptide, including membrane binding, interactions with insulin as well as the interaction between C-peptide and zinc and effects on microvascular vasoreactivity. The third section summarizes in vivo animal studies of the type 1 diabetic complications. The fourth section reviews the clinical efforts of C-peptide on inflammation, cardiovascular complication, neuropathy and nephropathy. Finally, in the Conclusions section, a summary of the present state of C-peptide, outstanding questions, and the likely direction of the field are offered. Developed by the foremost investigators in the rapidly moving field of C-peptide research, Diabetes & C-Peptide: Scientific and Clinical Aspects is an important contribution to the literature for all researchers and physicians concerned about type 1 diabetes. ER -