TY - BOOK ID - 14220883 TI - T Lymphocytes as Tools in Diagnostics and Immunotoxicology PY - 2014 SN - 3034807252 3034807260 PB - Basel : Springer Basel : Imprint: Springer, DB - UniCat KW - Immunology. KW - Medical laboratories. KW - Medicine. KW - Clinical sciences KW - Medical profession KW - Immunobiology KW - Laboratory medicine. KW - Molecular biology. KW - Biomedicine. KW - Molecular Medicine. KW - Laboratory Medicine. KW - Human biology KW - Life sciences KW - Medical sciences KW - Pathology KW - Physicians KW - Serology KW - Diagnosis, Laboratory KW - Health facilities KW - Laboratories KW - Health Workforce KW - Clinical medicine KW - Clinical pathology KW - Diagnostic laboratory tests KW - Laboratory diagnosis KW - Laboratory medicine KW - Medical laboratory diagnosis KW - Diagnosis KW - Molecular biochemistry KW - Molecular biophysics KW - Biochemistry KW - Biophysics KW - Biomolecules KW - Systems biology KW - Medicine KW - Biology KW - Biomedical Research. KW - Research. KW - Biological research KW - Biomedical research UR - https://www.unicat.be/uniCat?func=search&query=sysid:14220883 AB - This book summarizes the state-of-the art in the development of T cell-based in vitro assays, which offer useful tools for hazard identification, risk assessment and improvement of diagnostics. It will be of interest to scientists, the chemical and pharmaceutical industry, and regulators involved in the replacement of animal testing methods. The identification of hazardous chemicals and drugs is essential to ensuring human health. The ban on animal testing for the cosmetics industry since 2009 and international efforts to reduce and replace animal testing in research and immunotoxicology call for alternative in vitro methods. The most specific immune response to chemicals and drugs that cause allergic contact dermatitis, respiratory disease and adverse drug reactions is the highly antigen-specific T lymphocyte response. Therefore the use of T cells as tools for identifying contact allergens and drugs that may cause health problems is of great interest. ER -