TY - BOOK ID - 142208511 TI - Syncytia: Origin, Structure, and Functions AU - Kloc, Malgorzata. AU - Uosef, Ahmed. PY - 2024 SN - 3031379365 PB - Cham : Springer International Publishing : Imprint: Springer, DB - UniCat KW - Cell differentiation. KW - Developmental biology. KW - Stem cells. KW - Cytology. KW - Cell Differentiation. KW - Developmental Biology and Stem Cells. KW - Stem Cell Biology. KW - Cell Biology. UR - https://www.unicat.be/uniCat?func=search&query=sysid:142208511 AB - This book gives a current overview on the development, origin, structure, and functions of germline and somatic cell syncytia during embryogenesis and organogenesis. It also reviews pathogen-induced syncytia and the role of syncytial cells in cancer development. The book covers the following topics: germline syncytia, evolution, function and structure; syncytia in embryogenesis and development; the role of somatic cell fusion in fungi, specialized somatic tissues, host defense and adaptation; syncytia induced by viruses and parasites; syncytia and circulating hybrid cells in cancer and other pathological conditions; It also discusses how the genomic adaptations of microorganisms to extreme habitats can prompt the evolution of mononuclear and multinucleate/syncytial cells. The book offers a fresh outlook on syncytia's role in various processes: embryogenesis, organogenesis, adaptation, host defense, and development of specialized tissues. It highlights the importance of syncytia under physiological and pathological conditions. ER -