TY - THES ID - 139136543 TI - Three-dimensional evaluation of secondary alveolar bone grafting in patients with unilateral cleft lip and palate: 2-3 year post-operative follow-up AU - Doucet, Kaat AU - Cadenas de Llano Perula, Maria AU - Willems, Guy AU - Verdonck, Anna AU - KU Leuven. Faculteit Geneeskunde. Opleiding Master in de specialistische mondzorg (Leuven) PY - 2023 PB - Leuven KU Leuven. Faculteit Geneeskunde DB - UniCat UR - https://www.unicat.be/uniCat?func=search&query=sysid:139136543 AB - Abstract Objectives: The present study aims (1) to quantitatively assess secondary alveolar bone graft (SABG) resorption in 3D of unilateral cleft lip and palate (UCLP) patients in a 2-3 year longitudinal follow-up and (2) to study the potential relation of SABG resorption with maxillary canine position and with (3) a number of patient-related factors. Methods: UCLP patients who underwent SABG and had good quality CBCT images at the following timepoints: preoperative (T0), immediate (T1), 6 months (T2) and either 1-2 years (T3) or 2-3 years (T4) postoperative. The final bone grafted region (FBGR) was defined on the T1 scans and refined in the registered T0 scans. The residual bone graft was calculated by applying threshold-based segmentation on the registered T2, T3 or T4 scans within the segmented bone graft volume. This resulted into the bone graft after resorption (BGAR). The position of the canines was determined at every time point, at the cleft and non-cleft side. Results: Forty-five UCLP patients (mean age 9.0±1.3 years) were included. 43,6% bone resorption was found in the first 6 months after SABG. 1-2 years after SABG, 56,0% and 42,7% bone resorption was found if the maxillary canine was not yet erupted and erupted through the graft. The vertical position of the canines was significantly higher on the cleft side at T3. Conclusions: Although the SABG resorbs significantly over time, no correlation was found between SABG resorption and canine position neither between other patient-related factors. Further research could analyze the effect of oral hygiene on SABG resorption. ER -