TY - BOOK ID - 138998729 TI - Intraocular Pressure and Ocular Hypertension AU - Brusini, Paolo AU - Salvetat, Maria Letizia AU - Zeppieri, Marco PY - 2022 PB - Basel MDPI Books DB - UniCat KW - intraocular pressure KW - serum calcium KW - female KW - ab interno trabeculotomy KW - glaucoma KW - incision in the Schlemm’s canal in degrees KW - post-surgical complication KW - neuroretinal rim reversal KW - Bruch’s membrane opening-minimum rim width KW - trabeculectomy KW - refractive error KW - neuroretina KW - myopia KW - intraocular pressure (IOP) KW - tonometry KW - Goldmann applanation tonometer (GAT) KW - central corneal thickness (CCT) KW - ocular hypertension KW - higher-order aberrations KW - Kahook Dual Blade KW - age KW - central corneal thickness KW - Goldmann Applanation tonometer KW - non-contact tonometer KW - rebound tonometer KW - iCare KW - open angle glaucoma (OAG) KW - Schlemm’s canal viscodilation KW - OMNI viscosurgical system KW - minimally invasive glaucoma surgeries (MIGS) KW - trabeculotomy KW - cataract extraction KW - aqueous humor KW - GDF15 KW - serum KW - intravitreal injection KW - anti-VEGF agents KW - trabecular meshwork KW - Matrigel KW - 3D culture KW - outflow KW - cytoskeleton KW - rho-kinase inhibitor KW - prostaglandin analog KW - childhood glaucoma KW - aphakia KW - pseudophakia KW - cataract surgery KW - lensectomy KW - management (or therapy) KW - glaucoma drainage device KW - cyclodestruction KW - corneal biomechanics KW - ocular response analyzer KW - ORA KW - corneal hysteresis KW - non-penetrating deep sclerectomy KW - Esnoper V-2000 implant KW - glucocorticoids KW - safety profile KW - intranasal administration KW - inhaled administration KW - systemic administration KW - steroid response KW - canaloplasty KW - non-perforating surgical procedures KW - pseudoexfoliation glaucoma (PEXG) KW - Schlemm’s canal KW - phase-sensitive optical coherent tomography KW - pulsatile motion KW - IOP fluctuation KW - primary open-angle glaucoma KW - intraocular pressure measurement KW - iCare tonometry KW - Perkins tonometry KW - standardized anaesthesia KW - corneal thickness KW - progression KW - risk stratification KW - XEN GelStent KW - corneal resistance factor KW - open-angle glaucoma KW - n/a KW - laser treatment KW - dropless treatment KW - thyroid-associated ophthalmopathy KW - extraocular muscle KW - magnetic resonance imaging KW - T2 relaxation time KW - incision in the Schlemm's canal in degrees KW - Bruch's membrane opening-minimum rim width KW - Schlemm's canal viscodilation KW - Schlemm's canal UR - https://www.unicat.be/uniCat?func=search&query=sysid:138998729 AB - Primary open-angle glaucoma (POAG) is a multi-factorial progressive optic neuropathy characterized by retinal ganglion cell degeneration and progressive visual field loss which, if left untreated, may lead to blindness. Increased intraocular pressure (IOP) is considered to be the main risk factor for developing POAG, and its reduction has been shown to correlate with a decrease in glaucoma incidence and progression. Considering that fewer than 10% of the subjects with ocular hypertension (OHT) will develop morphological and/or functional glaucomatous damage within 5 years if not treated, glaucoma causes and molecular changes leading to ocular tissue damage in glaucoma are still largely unknown. The contemporary treatment of POAG is mainly oriented towards reducing IOP; the importance of the IOP reduction in other types of glaucoma, such as the “normal pressure glaucoma”, is still discussed. The IOP value is maintained by balancing the amount of fluid contained within the anterior and posterior chambers of the eye; our comprehension of the mechanisms underlying the secretion and active and passive outflow of the aqueous humor is extremely important for improving the treatment of glaucoma. Innovative pharmacological approaches, and laser and surgical procedures aiming to reduce IOP, have been developed in recent years. This book provides a compendium of topics regarding IOP, aqueous humor dynamics, tonometry, and medical and surgical techniques developed to reduce the IOP in subjects with ocular hypertension or glaucoma. ER -