TY - BOOK ID - 138343039 TI - MicroRNAs in development and cancer PY - 2011 SN - 1283143321 9786613143327 1848163673 9781848163676 9781283143325 6613143324 9781848163669 1848163665 PB - London Singapore Imperial College Press World Scientific [distributor] DB - UniCat KW - Cancer KW - Small interfering RNA. KW - Genetic aspects. UR - https://www.unicat.be/uniCat?func=search&query=sysid:138343039 AB - MicroRNAs have recently emerged as key regulators of gene expression during development and are frequently misexpressed in human disease states, in particular cancer. These 22-nucleotide-long transcripts act to promote or repress cell proliferation, migration and apoptosis during development, all of which are processes that go awry in cancer. Thus, microRNAs have the ability to behave like oncogenes or tumor suppressors. In addition, their small size and molecular properties make them amenable as targets and therapeutics in cancer treatment. This book goes into detail on how microRNAs represen ER -