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TY  - BOOK
ID  - 138336050
TI  - Toxicological Effects of Mycotoxins on Target Cells
PY  - 2020
PB  - Basel, Switzerland MDPI - Multidisciplinary Digital Publishing Institute
DB  - UniCat
KW  - Destruxin A
KW  - Bombyx mori
KW  - binding protein
KW  - BmTudor-sn
KW  - Bm12 cell
KW  - Ochratoxin A (OTA)
KW  - human Stem Cells
KW  - mycotoxins
KW  - cells
KW  - cytotoxicity
KW  - cell culture
KW  - T-2 toxin
KW  - HT-2 toxin
KW  - apoptosis
KW  - autophagy
KW  - endophyte
KW  - fungi
KW  - neurotoxin
KW  - lolitrems
KW  - ochratoxin A
KW  - beauvericin
KW  - mixtures
KW  - HepG2 cells
KW  - genotoxicity
KW  - cell cycle
KW  - Fusarium
KW  - Aspergillus
KW  - Penicillium
KW  - Alternaria
KW  - emerging mycotoxin
KW  - in vitro
KW  - IPEC-J2
KW  - occurrence data
KW  - trichothecene
KW  - biosynthetic pathway
KW  - acetyltransferase
KW  - deacetylase
KW  - deoxynivalenol
KW  - 3-acetyldeoxynivalenol
KW  - isotrichodermol
KW  - isotrichodermin
KW  - differentiated Caco-2 cells
KW  - cell apoptosis
KW  - transcriptome analysis
KW  - hepatocyte
KW  - chicken
KW  - acute toxicity
KW  - combined toxicity
KW  - cell protection
KW  - silibinin
KW  - in silico prediction
KW  - co-culture models
KW  - mycotoxin interaction
KW  - Loewe additivity
KW  - combination index
KW  - isobologram
KW  - Chou-Talalay method
KW  - MixLow
KW  - IPEC-J2 cells
KW  - RNA-seq
KW  - inflammation
KW  - MAPKs
KW  - n/a
KW  - Medicine.
UR  - https://www.unicat.be/uniCat?func=search&query=sysid:138336050
AB  - Mycotoxins are a Public Health concern that in last year have reached the top 10 food and product hazard categories in the Rapid Alert System for Food and Feed (RASFF), with almost six hundred notifications. The toxicological effects of mycotoxins are evaluated through the extrapolation of results from in vivo and in vitro assays. Studies of mycotoxins’ effects at the cellular level precede those in organs and systems. All these studies are key steps for risk assessment and following legislation for mycotoxins. This Special Issue of Toxins comprises 10 original contributions and two reviews. The Issue reports new findings regarding toxic mechanisms, the use of innovative techniques to study the potential toxicity of mycotoxins not only individually but in combination, reflecting a real scenario according to current studies of mycotoxins.
ER  -