TY - BOOK ID - 137419536 TI - Kidney Inflammation, Injury and Regeneration 2020 AU - Baer, Patrick C. AU - Koch, Benjamin AU - Geiger, Helmut PY - 2021 PB - Basel, Switzerland MDPI - Multidisciplinary Digital Publishing Institute DB - UniCat KW - inflammation KW - chronic kidney disease KW - anemia KW - anemia of inflammation KW - ESA hyporesponsiveness KW - renal tubular epithelial cells KW - macrophages KW - lipocalin-2 KW - iron KW - cilastatin KW - hypoxia inducible factor-1-α KW - ischemia-reperfusion injury KW - acute kidney injury KW - cyclophilin A KW - fibrosis KW - renal fibrosis KW - tubular necrosis KW - preeclampsia KW - podocytes KW - VEGF KW - FSGS KW - proteinuria KW - endocan KW - ESM-1 KW - renal replacement therapy KW - kidney transplantation KW - biomarker KW - diabetic nephropathy KW - focal segmental glomerulosclerosis KW - innate immunity KW - membranous nephropathy KW - minimal change diseases KW - TLR KW - NOX1 KW - ML171 KW - reactive oxygen species KW - ERK KW - T cells KW - glomerulonephritis KW - chemokines KW - renal disease KW - DJ-1 KW - ND-13 KW - renal inflammation KW - oxidative stress KW - UUO KW - autophagy KW - apoptosis KW - trehalose KW - simvastatin KW - endotoxin KW - tubular apoptosis KW - cytochrome C KW - Bcl-XL KW - survivin KW - hypercholesterolemia KW - xanthine oxidase KW - NF-κB pathway KW - tertiary lymphoid organs KW - B cells KW - BAFF KW - kidney fibrosis KW - myofibroblast activation KW - extracellular matrix KW - Hippo pathway KW - verteporfin KW - IgAN KW - CKD KW - progression KW - ACEI KW - corticosteroids KW - costimulation KW - coinhibition KW - kidney transplant KW - SPR KW - protein binding affinity KW - adaptive immunity KW - epithelial-to-mesenchymal transition KW - E. cava extracts KW - dieckol KW - spontaneously hypertensive rats KW - angiotensin II KW - n/a UR - https://www.unicat.be/uniCat?func=search&query=sysid:137419536 AB - Acute kidney injury (AKI) is still associated with high morbidity and mortality incidence rates, and also bears an elevated risk of chronic kidney disease in the sequel. Whereas the kidney has a remarkable capacity for regeneration after injury and may recover completely depending on the type of renal lesions, the options for clinical intervention are restricted to fluid management and extracorporeal kidney support. The development of novel therapies to prevent AKI, to improve renal regeneration capacity after AKI, and to preserve renal function—in both the short- and long-term—is urgently needed. This Special Issue includes papers investigating the pathological mechanisms of renal inflammation and AKI and diagnostics using new biomarkers. Furthermore, experimental in vitro and in vivo studies examining potential new approaches to attenuate kidney dysfunction are included, as well as review articles. ER -