TY - BOOK ID - 137331861 TI - Recent Developments in Cancer Systems Biology AU - Sinha, Raghu AU - Arga, Kazim Yalcin PY - 2021 PB - Basel, Switzerland MDPI - Multidisciplinary Digital Publishing Institute DB - UniCat KW - Sestrin2 KW - lung cancer KW - knockdown KW - cancer progression KW - bioinformatics KW - patient survival KW - lung adenocarcinoma KW - circulating miR-1246 KW - glycosaminoglycan binding KW - prognosis KW - PI3K–Akt signaling pathways KW - TargetScan KW - UBE2C KW - cancer systems biology KW - experimental model systems KW - next-generation sequencing KW - single-cell sequencing KW - patient-derived xenografts KW - patient-derived organoids KW - triple-negative breast cancer KW - personalized medicine KW - computational methods KW - drug repurposing KW - clinical trials KW - cancer stem cells KW - ETS KW - Elk-1 KW - stem cell KW - microarray KW - brain-tumor-initiating cell (BTIC) KW - pancreatic cancer KW - systems biology KW - omics KW - biomarker KW - genomics KW - transcriptomics KW - proteomics KW - metabolomics KW - glycomics KW - metagenomics KW - Ets KW - PEA3 KW - Ets-1 KW - glioma KW - optical genome mapping KW - solid tumors KW - cancer genomics KW - breast KW - ovarian KW - cancer KW - TCGA KW - non-small-cell lung cancer KW - lung adenocarcinoma (LUAD) KW - lung squamous cell carcinoma (LUSC) KW - differential expression KW - SNV KW - CNV KW - risk group KW - signature KW - survival KW - renal cancers KW - protein interactome KW - diagnostic biomarker KW - prognostic biomarker KW - virtual screening KW - docking KW - acute myeloid leukemia KW - Boolean model KW - drug resistance KW - network KW - n/a KW - PI3K-Akt signaling pathways UR - https://www.unicat.be/uniCat?func=search&query=sysid:137331861 AB - This ebook includes original research articles and reviews to update readers on the state of the art systems approach to not only discover novel diagnostic and prognostic biomarkers for several cancer types, but also evaluate methodologies to map out important genomic signatures. In addition, therapeutic targets and drug repurposing have been emphasized for a variety of cancer types. In particular, new and established researchers who desire to learn about cancer systems biology and why it is possibly the leading front to a personalized medicine approach will enjoy reading this book. ER -