TY - BOOK ID - 135546168 TI - Babesia and Human Babesiosis AU - Montero, Estrella AU - Gray, Jeremy AU - Lobo, Cheryl Ann AU - González, Luis Miguel PY - 2022 PB - Basel MDPI - Multidisciplinary Digital Publishing Institute DB - UniCat KW - babesiosis KW - Babesia microti KW - Babesia duncani KW - parasite KW - therapy KW - atovaquone KW - endochin-like quinolones (ELQs) KW - human babesiosis KW - Nantucket Island KW - epidemiology KW - ecology KW - human risk KW - European babesiosis KW - Babesia divergens KW - Babesia venatorum KW - Ixodes ricinus KW - parasite identity KW - clinical cases KW - diagnosis KW - treatment KW - Babesia KW - diversity KW - phylogenetic analysis KW - blood transfusion KW - prevention KW - screening KW - aspartyl protease KW - plasmepsin KW - apicomplexa KW - piroplasmida KW - BmIPA48 KW - BMR1_03g00960 KW - piroplasmid rhoptry-associated protein-1 (pRAP-1) KW - ticks KW - Babesia sp. KW - biological cycle KW - experimental transmission KW - experimental models KW - Ixodes scapularis KW - climate KW - global warming KW - Babesia sp. MO1 KW - Babesia capreoli KW - rap-1a KW - ama-1 KW - phylogeny KW - sickle-cell anemia KW - hemolysis KW - haemoglobinopathies KW - immunoepidemiology KW - case surveillance KW - therapeutic drugs KW - peptidases KW - antibody-based assays KW - nucleic acid tests KW - multiplex detection KW - next generation sequencing KW - glycosylphosphatidylinositol KW - protein structure KW - antigen KW - host blood analysis KW - fallow deer KW - ixodid ticks KW - piroplasm KW - red deer KW - Theileria KW - Babesia bovis KW - Babesia bigemina KW - Colombia KW - n/a KW - in vitro culture KW - erythrocytes KW - DMEM-F12 KW - virulence UR - https://www.unicat.be/uniCat?func=search&query=sysid:135546168 AB - Babesiosis, caused by tick-transmitted intraerythrocytic parasites (Babesia spp.), occurs worldwide. The disease mainly affects livestock, but records of infections in humans are increasing, and the disease is considered to be emerging worldwide. This book provides a comprehensive and holistic view of Babesia species that can infect humans. Numerous experts analyze, in detail, basic aspects of the biology of Babesia, the pathology of the babesiosis highlighting the pathogenesis of babesiosis in sickle cell, the eco-epidemiology of tick vectors and the impact of climate change on them, the current status, and future prospects for laboratory diagnosis and measures to prevent transfusion transmission. The book also focused on unidentified Babesia parasites that continue to emerge, most likely from wildlife, for which neither tick vector species nor vertebrate reservoir host species are currently known. Lastly, current and new therapies for infected patients, in vitro and in vivo culture systems for antibabesial evaluation and measures to prevent infections are also considered. ER -