TY - BOOK ID - 135280446 TI - New Insights into the Pathogenesis and Therapies of IgA Nephropathy AU - Suzuki, Hitoshi AU - Novak, Jan PY - 2022 PB - Basel MDPI Books DB - UniCat KW - obesity KW - mesangial matrix expansion KW - body mass index KW - IgA nephropathy KW - IgA Vasculitis KW - IgA Nephropathy KW - adults KW - children KW - presentation KW - physiopathology KW - genetics KW - prognosis KW - treatment KW - IgA KW - clinical trials KW - kidney mesangium KW - mouse model KW - aberrantly glycosylated IgA1 KW - galactose-deficient IgA1 KW - glycosylation of IgA1 KW - biomarker KW - complement C3 KW - O-glycosylation KW - IgA1 KW - autoantibody KW - immune complex KW - complement KW - kidney KW - nephrology KW - IgA vasculitis KW - nephritis KW - kidney biopsy KW - plasma cells KW - CD38 KW - renal pathology KW - urinary galactose-deficient IgA1 KW - KM55 KW - crescents KW - proteinuria KW - glomerular filtration rate KW - Oxford score KW - n/a UR - https://www.unicat.be/uniCat?func=search&query=sysid:135280446 AB - IgA nephropathy (IgAN) is the most common form of primary glomerulonephritis worldwide and a frequent cause of kidney failure. Better understanding of the pathogenesis of IgAN and the related genetic, immunological, and cellular susceptibility factors are needed to enable the development of effective disease-specific therapy. This book brings together international experts to provide clinical and experimental studies and reviews with an emphasis on early diagnosis, prognosis, disease pathogenesis, determination of disease activity, and new strategies for treatment for IgAN. ER -