TY - BOOK ID - 134624791 TI - Pathogenesis and Treatment of Chronic Pruritus PY - 2020 PB - Basel, Switzerland MDPI - Multidisciplinary Digital Publishing Institute DB - UniCat KW - dupilumab KW - IL-4 KW - IL-13 KW - pruritus KW - chronic pruritus of unknown origin KW - prurigo nodularis KW - uremic pruritus KW - lichen planus KW - eosinophilic dermatosis of hematologic malignancy KW - chronic pruritus KW - mirtazapine KW - chronic KW - itch KW - refractory KW - treatment KW - noradrenergic KW - serotonergic KW - antihistaminergic KW - antidepressant KW - skin KW - atopic dermatitis KW - ceramide KW - pine tar KW - drug-induced KW - medication-related KW - epidemiology KW - inpatient KW - disease burden KW - national inpatient sample KW - medical dermatology KW - systematic review KW - prurigo KW - nodularis KW - atopic KW - dermatitis KW - race KW - gender KW - comorbidities KW - demographics KW - pediatric KW - children KW - malignancy KW - cancer KW - neoplasm KW - ion channels KW - cell signaling KW - Cav3.2 calcium channel KW - RT-PCR KW - wounds KW - itch in wounds KW - itch management KW - aprepitant KW - erlotinib KW - EGFR KW - epidermal growth factor receptor KW - NK1R KW - neurokinin1-receptor KW - mycosis fungoides KW - psoriasis KW - associations KW - lymphomatoid papulosis KW - lymphoma KW - racial differences KW - nodular prurigo KW - neuropathy KW - therapeutic KW - pathogenesis UR - https://www.unicat.be/uniCat?func=search&query=sysid:134624791 AB - This Special Edition Issue on the “Pathogenesis and Treatment of Chronic Pruritus” contains an overview of various known causes of chronic pruritus and emerging therapeutics. Chronic pruritus is an itch that lasts longer than six weeks, and is associated with a variety of dermatologic, systemic, neurologic, and psychiatric etiologies. Itch negatively impacts patient quality of life, and has devastating psychosocial consequences. The manuscripts published in this Special Issue are also a showcase of the current understanding of the pathogenesis of chronic pruritus, along with its epidemiology, diagnostic workup, and therapeutic approaches used to treat chronic pruritus. A special focus is also placed on prurigo nodularis, a severely pruritic chronic inflammatory skin disease. ER -