TY - BOOK ID - 134239666 TI - Neuropeptide GPCRs in neuroendocrinology AU - Jae Young Seong AU - Vaudry, Hubert AU - Seong, Jae Young PY - 2014 PB - Frontiers Media SA DB - UniCat KW - Neuroendocrinology. KW - Neuropharmacology. KW - Endocrinology. KW - Animal Biochemistry KW - Human Anatomy & Physiology KW - Health & Biological Sciences KW - Transduction pathways KW - G protein-coupled receptors KW - Neuroendocrinology KW - Heptahelical receptors KW - Neuropeptides KW - Signaling mechanisms KW - Biologically active peptides KW - seven-transmembrane domain receptors UR - https://www.unicat.be/uniCat?func=search&query=sysid:134239666 AB - The human genome encompasses ≈ 860 G protein-coupled receptors (GPCRs) including 374 non-chemosensory GPCRs. Half of these latter GPCRs recognize (neuro)peptides as natural ligands. GPCRs thus play a pivotal role in neuroendocrine communication. In particular, GPCRs are involved in the neuroendocrine control of feeding behavior, reproduction, growth, hydromineral homeostasis and stress response. GPCRs are also major drug targets and hence possess a strong potential for the development of innovative pharmaceuticals. The aim of this Research Topic is to assemble a series of review articles and original research papers on neuropeptide GPCRs and their ligands that will illustrate the different facets of the studies currently conducted in this domain. ER -